[HTML][HTML] Proteomics and peptidomics: moving toward precision medicine in urological malignancies

A Di Meo, MD Pasic, GM Yousef - Oncotarget, 2016 - ncbi.nlm.nih.gov
Urological malignancies are a major cause of morbidity and mortality worldwide. Advances
in early detection, diagnosis, prognosis and prediction of treatment response can …

Stable isotope dimethyl labelling for quantitative proteomics and beyond

JL Hsu, SH Chen - … Transactions of the Royal Society A …, 2016 - royalsocietypublishing.org
Stable-isotope reductive dimethylation, a cost-effective, simple, robust, reliable and easy-to-
multiplex labelling method, is widely applied to quantitative proteomics using liquid …

A single-cell survey of cellular hierarchy in acute myeloid leukemia

J Wu, Y Xiao, J Sun, H Sun, H Chen, Y Zhu… - Journal of hematology & …, 2020 - Springer
Background Acute myeloid leukemia (AML) is a fatal hematopoietic malignancy and has a
prognosis that varies with its genetic complexity. However, there has been no appropriate …

SH3BGRL2 inhibits growth and metastasis in clear cell renal cell carcinoma via activating hippo/TEAD1-Twist1 pathway

L Yin, W Li, A Xu, H Shi, K Wang, H Yang, R Wang… - …, 2020 - thelancet.com
Background Clear cell renal cell carcinoma (ccRCC) is one of the most prevalent
malignancies in the world, and tumor metastasis is still the main reason for disease …

[HTML][HTML] LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1

S Logotheti, S Marquardt, SK Gupta, C Richter… - Theranostics, 2020 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) have emerged as integral components of E2F1-regulated
gene regulatory networks (GRNs), but their implication in advanced or treatment-refractory …

Substrate specificity of thioredoxins and glutaredoxins–towards a functional classification

M Gellert, MF Hossain, FJF Berens, LW Bruhn… - Heliyon, 2019 - cell.com
The spatio-temporal reduction and oxidation of protein thiols is an essential mechanism in
signal transduction in all kingdoms of life. Thioredoxin (Trx) family proteins efficiently …

Small extracellular vesicles promote invadopodia activity in glioblastoma cells in a therapy-dependent manner

CA Whitehead, H Fang, H Su, AP Morokoff, AH Kaye… - Cellular Oncology, 2023 - Springer
Purpose The therapeutic efficacy of radiotherapy/temozolomide treatment for glioblastoma
(GBM) is limited by the augmented invasiveness mediated by invadopodia activity of …

[HTML][HTML] Proteomic analysis of plasma exosomes in patients with non-small cell lung cancer

M Bao, Y Huang, Z Lang, H Zhao, Y Saito… - … lung cancer research, 2022 - ncbi.nlm.nih.gov
Background Currently, the prognosis of patients with non-small cell lung cancer (NSCLC)
remains unsatisfactory. This current study evaluated the relationship between histology of …

Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway

M Seervi, S Sumi, A Chandrasekharan, AK Sharma… - Cellular Oncology, 2019 - Springer
Purpose Anastasis is newly discovered process by which cells recover from late-stage
apoptosis upon removal of a death stimulus. Recent reports suggest that cells may recover …

Significance of stress keratin expression in normal and diseased epithelia

E Cohen, CN Johnson, R Wasikowski, AC Billi, LC Tsoi… - Iscience, 2024 - cell.com
A group of keratin intermediate filament genes, the type II KRT6A-C and type I KRT16 and
KRT17, are deemed stress responsive as they are induced in keratinocytes of surface …