With the development of NMR methodology and technology during the past decades, solid-
state NMR (ssNMR) has become a particularly important tool for investigating structure and …

Much of postgenomic biochemistry and all of structural biology are based on the premise
that the starting point for both understanding specific biochemical processes, such as affinity …

NMR is a versatile tool for studying interactions between antimicrobial peptides and lipid
membranes. Different approaches using both liquid state and solid state NMR are outlined …

The membrane alignment of the amphiphilic α-helical model peptide MSI-103 (sequence
[KIAGKIA] 3-NH2) was examined by solid state 2H-NMR in different lipid systems by …

At first sight the application of 19F NMR to biological samples may seem like a paradox, as
fluorine scarcely occurs in organic matter. However, this very lack of natural abundance in …

The membrane-disruptive antimicrobial peptide PGLa is found to change its orientation in a
dimyristoyl-phosphatidylcholine bilayer when its concentration is increased to biologically …

The branching coral Acropora palmata is a foundation species of Caribbean reefs that has
been decimated in recent decades by anthropogenic and natural stressors. Declines in …

The interaction of membranes with peptides and proteins is largely determined by their
amphiphilic character. Hydrophobic moments of helical segments are commonly derived …

The location of proline (Pro) in proteins is peculiar: it is most frequently found in loops, turns,
and flanking positions of stable secondary-structure elements.[1] Such positioning is a …

The antimicrobial activity of amphipathic α-helical peptides is usually attributed to the
formation of pores in bacterial membranes, but direct structural information about such a …