The many roles of tranexamic acid: an overview of the clinical indications for TXA in medical and surgical patients

J Cai, J Ribkoff, S Olson… - European journal of …, 2020 - Wiley Online Library
Clinically significant bleeding can occur as a consequence of surgery, trauma, obstetric
complications, anticoagulation, and a wide variety of disorders of hemostasis. As the causes …

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

H Döhner, EH Estey, S Amadori… - Blood, The Journal …, 2010 - ashpublications.org
In 2003, an international working group last reported on recommendations for diagnosis,
response assessment, and treatment outcomes in acute myeloid leukemia (AML). Since that …

Tranexamic acid evidence and controversies: an illustrated review

N Relke, NLJ Chornenki… - Research and practice in …, 2021 - Wiley Online Library
Tranexamic acid (TXA) is an antifibrinolytic agent commonly used for the treatment or
prevention of bleeding. Indications for TXA are diverse, including heavy menstrual bleeding …

Management of bleeding in patients with advanced cancer

J Pereira, T Phan - The oncologist, 2004 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to: List at
least four local hemostatic agents and dressings for controlling localized bleeding in a …

Thrombocytopenia in cancer patients

HA Liebman - Thrombosis research, 2014 - Elsevier
Thrombocytopenia is a frequent complication of cancer and its treatment. The causes of
thrombocytopenia in cancer patients can be diverse and multifactorial. Systemic …

Risk of venous and arterial thrombosis in non-surgical patients receiving systemic tranexamic acid: a systematic review and meta-analysis

NLJ Chornenki, KJ Um, PA Mendoza… - Thrombosis research, 2019 - Elsevier
Background Antifibrinolytic agents such as tranexamic acid (TXA) are commonly used as
adjunctive therapies to prevent and treat excessive bleeding. In non-surgical settings, TXA is …

Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disorders

LJ Estcourt, M Desborough, SJ Brunskill… - Cochrane Database …, 2016 - cochranelibrary.com
Background People with haematological disorders are frequently at risk of severe or life‐
threatening bleeding as a result of thrombocytopenia (reduced platelet count). This is …

Effects of topical antifibrinolytics in endoscopic sinus surgery: a pilot randomized controlled trial

T Athanasiadis, AG Beule… - American journal of …, 2007 - journals.sagepub.com
Background Bleeding in endoscopic sinus surgery (ESS) may increase the risk of
intraoperative complications and is associated with poorer outcomes Antifibrinolytic agents …

[HTML][HTML] Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH

TF Wang, RS Makar, D Antic, JH Levy… - Journal of Thrombosis …, 2020 - Elsevier
Patients with acute leukemia frequently develop thrombocytopenia and hemostatic
complications caused by coagulopathy. Coagulopathy complicates the management of …

Challenges and advances in managing thrombocytopenic cancer patients

A Leader, L Hofstetter, G Spectre - Journal of clinical medicine, 2021 - mdpi.com
Cancer patients have varying incidence, depth and duration of thrombocytopenia. The
mainstay of managing severe chemotherapy-induced thrombocytopenia (CIT) in cancer is …