The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …

Tuberculosis (TB) lesions are extremely complex and dynamic. Here, we review the multiple
types and fates of pulmonary lesions that form following infection by M ycobacterium …

New technologies such as high-throughput methods and 13C-isotopologue-profiling
analysis are beginning to provide us with insight into the in vivo metabolism of …

The mycobacterial PE/PPE proteins have attracted much interest since their formal
identification just over a decade ago. It has been widely speculated that these proteins may …

Mycobacterium tuberculosis is a remarkable pathogen capable of adapting and surviving in
various harsh conditions. Correct gene expression regulation is essential for the success of …

One of the important determinants of virulence of Mycobacterium tuberculosis is adaptation
to adverse conditions encountered in the host cells. The ability of Mycobacterium to …

The Mycobacterium tuberculosis genome contains an unusually high number of toxin–
antitoxin modules, some of which have been suggested to play a role in the establishment …

During lung infection, Mycobacterium tuberculosis resides in macrophages and subverts the
bactericidal mechanisms of these professional phagocytes. Comprehension of this host …

Background Transcriptional profiling using microarrays provides a unique opportunity to
decipher host pathogen cross-talk on the global level. Here, for the first time, we have been …

Background COG0523 proteins are, like the nickel chaperones of the UreG family, part of the
G3E family of GTPases linking them to metallocenter biosynthesis. Even though the first …