Cell types are the basic building blocks of multicellular organisms and are extensively
diversified in animals. Despite recent advances in characterizing cell types, classification …

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide and is a risk
factor for dementia later in life. Research into the pathophysiology of TBI has focused on the …

Synapses are fundamental information-processing units of the brain, and synaptic
dysregulation is central to many brain disorders (" synaptopathies"). However, systematic …

A new theory about the origins of consciousness that finds learning to be the driving force in
the evolutionary transition to basic consciousness. What marked the evolutionary transition …

Genome-wide association studies on human behavioural traits are producing large amounts
of polygenic signals with significant predictive power and potentially useful biological clues …

Synucleinopathies, such as Parkinson's disease and dementia with Lewy bodies, are
neurodegenerative disorders that are characterized by the accumulation of α-synuclein …

Soluble amyloid-β oligomers (Aβo) trigger Alzheimer's disease (AD) pathophysiology and
bind with high affinity to cellular prion protein (PrP C). At the postsynaptic density (PSD) …

The greater expansion of the frontal lobes along the phylogeny scale has been interpreted
as the signature of evolutionary changes underlying higher cognitive abilities in humans …

Synapses are found in vast numbers in the brain and contain complex proteomes. We
developed genetic labeling and imaging methods to examine synaptic proteins in individual …

Recent large-scale genomic studies have revealed two broad classes of risk alleles for
schizophrenia: a polygenic component of risk mediated through multiple common risk …