Gemini surfactants provide a significant opportunity in the development of new non-viral
delivery systems designed for gene therapy applications. This review summarizes the wide …

Lipid-based drug carriers, such as liposomes or drug/lipid complexes, have been
extensively investigated in a large number of therapeutic protocols such as gene therapy …

This feature article describes the recent developments in the design of cationic lipids and
their applications in gene delivery. Various structure–activity investigations explaining the …

Hypothesis The positive charge on liposome surface is known to promote the crossing of the
Blood brain barrier (BBB). However, when diastereomeric cationic gemini amphiphiles are …

Antimicrobial photodynamic therapy is emerging as a promising therapeutic modality for
bacterial infections. For optimizing the antibacterial activity of the photosensitizer m …

The formation of calixarene-based liposomes was investigated, and the characterization of
these nanostructures was carried out using several techniques. Four amphiphilic …

Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a
number of challenging conditions, allowing researchers to cross barriers that have …

As a result of their unique physical properties, biological membrane mimetics, such as
liposomes, are used in a broad range of scientific and technological applications …

We report the design, synthesis, and characterization of a novel type of cationic lipopeptide,
gemini-like amphiphilic peptides or 'geminoids'. As an example, the SPKR peptide, inspired …

Background Increases in DNA transfection efficiencies for non‐viral vectors can be achieved
through rational design of novel cationic building blocks. Based on previous results …