[HTML][HTML] Levetiracetam modulates brain metabolic networks and transcriptomic signatures in the 5XFAD mouse model of Alzheimer's disease
Introduction Subcritical epileptiform activity is associated with impaired cognitive function
and is commonly seen in patients with Alzheimer's disease (AD). The anti-convulsant …
and is commonly seen in patients with Alzheimer's disease (AD). The anti-convulsant …
[HTML][HTML] In vivo reactive astrocyte imaging using [18F] SMBT-1 in tauopathy and familial Alzheimer's disease mouse models: A multi-tracer study
Y Kong, L Cao, J Wang, J Zhuang, F Xie, C Zuo… - Journal of the …, 2024 - Elsevier
Background Reactive astrocytes play an important role in the development of Alzheimer's
disease and primary tauopathies. Here, we aimed to investigate the relationships between …
disease and primary tauopathies. Here, we aimed to investigate the relationships between …
[PDF][PDF] Levetiracetam modulates brain
CP Burton, EJ Chumin, AY Collins, SA Persohn… - 2024 - scholarworks.indianapolis.iu.edu
Results: Pharmacokinetics of LEV showed a sex and dose dependence in Cmax, CL/F, and
AUC0-∞, with simulations used to estimate dose regimens. Chronic dosing at 10, 30, and …
AUC0-∞, with simulations used to estimate dose regimens. Chronic dosing at 10, 30, and …