Pathogenesis, epidemiology and control of Group A Streptococcus infection

S Brouwer, T Rivera-Hernandez, BF Curren… - Nature Reviews …, 2023 - nature.com
Abstract Streptococcus pyogenes (Group A Streptococcus; GAS) is exquisitely adapted to
the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or …

Correlates of immunity to Group A Streptococcus: a pathway to vaccine development

H Frost, JL Excler, S Sriskandan, A Fulurija - npj Vaccines, 2023 - nature.com
Understanding immunity in humans to Group A Streptococcus (Strep A) is critical for the
development of successful vaccines to prevent the morbidity and mortality attributed to Strep …

Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA

MR Davies, N Keller, S Brouwer, MG Jespersen… - Nature …, 2023 - nature.com
A new variant of Streptococcus pyogenes serotype M1 (designated 'M1UK') has been
reported in the United Kingdom, linked with seasonal scarlet fever surges, marked increase …

Increase in invasive group A streptococcal disease among Australian children coinciding with northern hemisphere surges

YN Abo, J Oliver, A McMinn, J Osowicki… - The Lancet Regional …, 2023 - thelancet.com
Background Increases in invasive group A streptococcal disease (iGAS) have recently been
reported in multiple countries in the northern hemisphere, occurring during, and outside of …

Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular …

NN Lynskey, E Jauneikaite, HK Li, X Zhi… - The Lancet Infectious …, 2019 - thelancet.com
Summary Background Since 2014, England has seen increased scarlet fever activity
unprecedented in modern times. In 2016, England's scarlet fever seasonal rise coincided …

Infectious diseases in children and adolescents in China: analysis of national surveillance data from 2008 to 2017

Y Dong, L Wang, DP Burgner, JE Miller, Y Song, X Ren… - bmj, 2020 - bmj.com
Objectives To outline which infectious diseases in the pre-covid-19 era persist in children
and adolescents in China and to describe recent trends and variations by age, sex, season …

Trends in pediatric ambulatory community acquired infections before and during COVID-19 pandemic: a prospective multicentric surveillance study in France

PR Cohen, A Rybak, A Werner, S Béchet… - The Lancet Regional …, 2022 - thelancet.com
Background Covid-19 pandemic control has imposed several non-pharmaceutical
interventions (NPIs). Strict application of these measures has had a dramatic reduction on …

[HTML][HTML] Emerging invasive group A Streptococcus M1UK lineage detected by allele-specific PCR, England, 2020

X Zhi, HK Li, H Li, Z Loboda, S Charles… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for
toxigenic lineage M1 UK. An allele-specific PCR was developed to distinguish M1 UK from …

Frequency of transmission, asymptomatic shedding, and airborne spread of Streptococcus pyogenes in schoolchildren exposed to scarlet fever: a prospective …

R Cordery, AK Purba, L Begum, E Mills… - The Lancet …, 2022 - thelancet.com
Background Despite recommendations regarding prompt treatment of cases and enhanced
hygiene measures, scarlet fever outbreaks increased in England between 2014 and 2018 …

Paediatric group A streptococcal disease in England from October to December, 2022

SN Ladhani, R Guy, SS Bhopal, CS Brown… - The Lancet Child & …, 2023 - thelancet.com
Since October, 2022, England has been experiencing a national increase in group A
streptococcal disease in children, including scarlet fever, pneumonia with empyema, and …