The psychosis high-risk state: a comprehensive state-of-the-art review
Context During the past 2 decades, a major transition in the clinical characterization of
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …
Developing psychosis and its risk states through the lens of schizotypy
Starting from the early descriptions of Kraepelin and Bleuler, the construct of schizotypy was
developed from observations of aberrations in nonpsychotic family members of …
developed from observations of aberrations in nonpsychotic family members of …
How effective are cognitive behavior therapies for major depression and anxiety disorders? A meta‐analytic update of the evidence
We report the current best estimate of the effects of cognitive behavior therapy (CBT) in the
treatment of major depression (MDD), generalized anxiety disorder (GAD), panic disorder …
treatment of major depression (MDD), generalized anxiety disorder (GAD), panic disorder …
Prediction models of functional outcomes for individuals in the clinical high-risk state for psychosis or with recent-onset depression: a multimodal, multisite machine …
N Koutsouleris, L Kambeitz-Ilankovic… - JAMA …, 2018 - jamanetwork.com
Importance Social and occupational impairments contribute to the burden of psychosis and
depression. There is a need for risk stratification tools to inform personalized functional …
depression. There is a need for risk stratification tools to inform personalized functional …
A critique of the “ultra‐high risk” and “transition” paradigm
J Van Os, S Guloksuz - World Psychiatry, 2017 - Wiley Online Library
The transdiagnostic expression of psychotic experiences in common mental disorder
(anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a …
(anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a …
Effect of ω-3 polyunsaturated fatty acids in young people at ultrahigh risk for psychotic disorders: the NEURAPRO randomized clinical trial
PD McGorry, B Nelson, C Markulev, HP Yuen… - JAMA …, 2017 - jamanetwork.com
Importance A promising treatment to prevent onset and improve outcomes in patients at
ultrahigh risk for psychosis is dietary supplementation with long-chain ω-3 polyunsaturated …
ultrahigh risk for psychosis is dietary supplementation with long-chain ω-3 polyunsaturated …
Trauma and recent life events in individuals at ultra high risk for psychosis: review and meta-analysis
Background Childhood trauma and recent life-events have been related to psychotic
disorders. The aim of the present study was to examine whether childhood trauma and …
disorders. The aim of the present study was to examine whether childhood trauma and …
Lessons learned from the psychosis high-risk state: towards a general staging model of prodromal intervention
BackgroundThe past two decades have seen exponential clinical and research interest in
help-seeking individuals presenting with potentially prodromal symptoms for psychosis …
help-seeking individuals presenting with potentially prodromal symptoms for psychosis …
Outreach and support in south London (OASIS), 2001–2011: ten years of early diagnosis and treatment for young individuals at high clinical risk for psychosis
P Fusar-Poli, M Byrne, S Badger, LR Valmaggia… - European …, 2013 - cambridge.org
Introduction: Prevention of psychosis has become a major objective of modern clinical
psychiatry. An increasing number of new services have been established in Europe and in …
psychiatry. An increasing number of new services have been established in Europe and in …
Attenuated psychosis syndrome in DSM-5
Despite advances in the treatment of schizophrenia over the past half-century, the illness is
frequently associated with a poor outcome. This is principally related to the late identification …
frequently associated with a poor outcome. This is principally related to the late identification …