Methotrexate an old drug with new tricks
Y Bedoui, X Guillot, J Sélambarom, P Guiraud… - International journal of …, 2019 - mdpi.com
Methotrexate (MTX) is the first line drug for the treatment of a number of rheumatic and non-
rheumatic disorders. It is currently used as an anchor disease, modifying anti-rheumatic drug …
rheumatic disorders. It is currently used as an anchor disease, modifying anti-rheumatic drug …
Side effects of methotrexate therapy for rheumatoid arthritis: A systematic review
W Wang, H Zhou, L Liu - European journal of medicinal chemistry, 2018 - Elsevier
Methotrexate (MTX) is used as an anchor disease-modifying anti-rheumatic drugs
(DMARDs) in treating rheumatoid arthritis (RA) because of its potent efficacy and tolerability …
(DMARDs) in treating rheumatoid arthritis (RA) because of its potent efficacy and tolerability …
Terpene compounds in nature: a review of their potential antioxidant activity
E Gonzalez-Burgos… - Current medicinal …, 2012 - ingentaconnect.com
Reactive Oxygen Species are involved in the pathological development of many important
human diseases such as neurodegenerative diseases, cardiovascular processes, diabetes …
human diseases such as neurodegenerative diseases, cardiovascular processes, diabetes …
Protective effect of Chlorogenic acid against methotrexate induced oxidative stress, inflammation and apoptosis in rat liver: An experimental approach
Methotrexate (MTX) is a drug which is used to treat different types of cancers but
hepatotoxicity limits its clinical use. Chlorogenic acid (CGA) is one of the most abundant …
hepatotoxicity limits its clinical use. Chlorogenic acid (CGA) is one of the most abundant …
The effect of β-carotene, tocopherols and ascorbic acid as anti-oxidant molecules on human and animal in vitro/in vivo studies: A review of research design and …
K Miazek, K Beton, A Śliwińska, B Brożek-Płuska - Biomolecules, 2022 - mdpi.com
Prolonged elevated oxidative stress (OS) possesses negative effect on cell structure and
functioning, and is associated with the development of numerous disorders. Naturally …
functioning, and is associated with the development of numerous disorders. Naturally …
Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats
AM Mahmoud, WG Hozayen, SM Ramadan - Biomedicine & …, 2017 - Elsevier
Berberine (BBR) is a natural isoquinoline alkaloid with very impressive health benefits. It is
one of the most effective natural supplements available; however, its ameliorative …
one of the most effective natural supplements available; however, its ameliorative …
[PDF][PDF] Ethanolic extract of capparis decidua fruit ameliorates methotrexate-induced hepatotoxicity by activating Nrf2/HO-1 and PPARγ mediated pathways
P Santhakumar, A Roy, KG Mohanraj… - Ind J Pharm …, 2021 - pdfs.semanticscholar.org
Introduction: Methotrexate, a folate antimetabolite, immunosuppressant and cytotoxic
chemotherapeutic agents employed for malignant conditions. Continuous exposure of …
chemotherapeutic agents employed for malignant conditions. Continuous exposure of …
Beneficial effects of Chrysin against Methotrexate-induced hepatotoxicity via attenuation of oxidative stress and apoptosis
Methotrexate (MTX), a folic acid antagonist, an effective chemotherapeutic agent is used in
the treatment of a wide range of tumors and autoimmune diseases. Moreover, hepatotoxicity …
the treatment of a wide range of tumors and autoimmune diseases. Moreover, hepatotoxicity …
Resveratrol ameliorates methotrexate-induced hepatotoxicity in rats via inhibition of lipid peroxidation
S Dalaklioglu, GE Genc, NH Aksoy… - Human & …, 2013 - journals.sagepub.com
Hepatotoxicity is one of the major complications of methotrexate (MTX) therapy. This study
was carried out to evaluate the possible protective effect of resveratrol (trans-3, 5, 4 …
was carried out to evaluate the possible protective effect of resveratrol (trans-3, 5, 4 …
[HTML][HTML] Commiphora molmol protects against methotrexate-induced nephrotoxicity by up-regulating Nrf2/ARE/HO-1 signaling
AM Mahmoud, MO Germoush, KM Al-Anazi… - Biomedicine & …, 2018 - Elsevier
Commiphora molmol possesses multiple therapeutic benefits against various diseases;
however, its protective role against methotrexate (MTX) renal toxicity has not been …
however, its protective role against methotrexate (MTX) renal toxicity has not been …