Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021 - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

A review of microfluidic-based mixing methods

Z Li, B Zhang, D Dang, X Yang, W Yang… - Sensors and Actuators A …, 2022 - Elsevier
Microfluidic-based mixing methods have aroused increasing attention due to their
tremendous potential in bio-related and materials science fields. Achieving mixing based on …

An overview on state-of-art of micromixer designs, characteristics and applications

X Wang, Z Liu, B Wang, Y Cai, Q Song - Analytica Chimica Acta, 2023 - Elsevier
Micromixers are characterized based on characteristics such as excellent mixing efficiency,
low reagent cost and flexible controllability compared with conventional reactors in terms of …

Fabrication of tunable, high-molecular-weight polymeric nanoparticles via ultrafast acoustofluidic micromixing

S Zhao, PH Huang, H Zhang, J Rich, H Bachman, J Ye… - Lab on a Chip, 2021 - pubs.rsc.org
High-molecular-weight polymeric nanoparticles are critical to increasing the loading efficacy
and tuning the release profile of targeted molecules for medical diagnosis, imaging, and …

Thorough computational analysis of the staggered herringbone micromixer reveals transport mechanisms and enables mixing efficiency-based improved design

AG Hadjigeorgiou, AG Boudouvis, G Kokkoris - Chemical Engineering …, 2021 - Elsevier
The problem of mixing of solutions of biomolecules in the famous staggered herringbone
micromixer (SHM) is revisited through a computational study with the focus on two …

An investigation of chaotic mixing behavior in a planar microfluidic mixer

S Yuan, M Zhou, T Peng, Q Li, F Jiang - Physics of Fluids, 2022 - pubs.aip.org
Achieving rapid mixing of different liquids in a short distance is important in various
biochemical applications. Herein, a novel planar mixer with staggered Z-shaped baffles is …

Numerical and experimental investigation of mixing enhancement in the passive planar mixer with bent baffles

S Yuan, B Jiang, F Jiang, D Drummer… - International Journal of …, 2022 - Elsevier
As an important pre-treatment part of the micro-total analysis system, the micromixer that
ensures the uniform mixing of samples and reagents in a short distance is essential for the …

A surface acoustic wave-assisted micromixer with active temperature control

C Bai, W Zhou, S Yu, T Zheng, C Wang - Sensors and Actuators A: Physical, 2022 - Elsevier
Microfluidic mixing is a critical issue in the lab-on-a-chip system, which has been applied in
various biomedical research. Recently, acoustic wave-based active micromixers have been …

Stackable micromixer with modular design for efficient mixing over wide Reynold numbers

S Zhu, Y Fang, Y Chen, P Yu, Y Han, N Xiang… - International Journal of …, 2022 - Elsevier
Fast and efficient micromixing of different species is crucial in many fields. However, most
previous micromixers can only achieve well mixing effects in a narrow Reynold number (Re) …

Design and application of a self-pumping microfluidic staggered herringbone mixer

RB Channon, RF Menger, W Wang, DB Carrão… - Microfluidics and …, 2021 - Springer
The rapid mixing of reagents is critical to a wide range of chemical and biological reactions
but is difficult to implement in microfluidic devices, particularly in capillary action/passive …