Ever since microRNAs (miRNAs) were first recognized as an extensive gene family> 20
years ago, a broad community of researchers was drawn to investigate the universe of small …

Small RNAs regulate a wide variety of biological processes by repressing the expression of
target genes at the transcriptional and post-transcriptional levels. To achieve these …

The development of animal embryos is initially directed by maternal gene products. Then,
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …

Production of sperm and androgens is the main function of the testis. This depends on
normal development of both testicular somatic cells and germ cells. A genetic program …

MicroRNAs (miRNAs) regulate the expression of most genes in animals, but we are only
now beginning to understand how they are generated, assembled into functional complexes …

Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …

Comparative genomics analyses and high-throughput experimental studies indicate that a
microRNA (miRNA) binds to hundreds of sites across the transcriptome. Although the …

With the advent of next generation sequencing techniques a previously unknown world of
non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely …

MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways.
These small non-coding RNAs bind to target sequences in mRNAs, typically resulting in …

The epitranscriptomic mark N 6-methyladenosine (m6A) can be written, read, and erased via
the action of a complex network of proteins. m6A binding proteins read m6A marks and …