Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) refer to a group of
heterogeneous cancers of neuroendocrine cell phenotype that mainly fall into one of two …

Cell lines originating from neuroendocrine tumors (NETs) represent useful experimental
models to assess the control of synthesis and release of different hormones and hormone …

Experimental models of neuroendocrine tumour disease are scarce, and no comprehensive
characterisation of existing gastroenteropancreatic neuroendocrine tumour (GEPNET) cell …

Small intestinal neuroendocrine tumors (SI-NETs) are slow-growing tumors that seem
genetically quite stable without highly recurrent mutations, but are epigenetically …

Ileal carcinoids are malignant neuroendocrine tumours of the small intestine. The aim of this
study was to obtain a high-resolution genomic profile of ileal carcinoids in order to define …

BACKGROUND & AIMS: Metastatic gastrointestinal neuroendocrine tumors (NETs)
frequently are refractory to chemotherapy. Chemoresistance in various malignancies has …

Aberrant DNA methylation is a feature of human cancer affecting gene expression and tumor
phenotype. Here, we quantified promoter methylation of candidate genes and global …

Recently, we discovered that transient receptor potential ankyrin1 channel (TRPA1) is highly
expressed in human and rat enterochromaffin (EC) cells, and those TRPA1 agonists such as …

Simple Summary Neuroendocrine neoplasia comprise many distinct and rare subtypes of
cancers. Preclinical models are essential for improving understanding of these diseases …

Expression of miRNAs in Neuroendocrine Neoplasms (NEN) is poorly characterized. We
therefore wanted to examine the miRNA expression in Neuroendocrine Tumors (NETs), and …