Melodic maestros: Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of malignant pleural mesothelioma

MA Abd-Elmawla, SSA Mageed… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly lethal form of pleural cancer
characterized by a scarcity of effective therapeutic interventions, resulting in unfavorable …

MiR-200, a new star miRNA in human cancer

X Feng, Z Wang, R Fillmore, Y Xi - Cancer letters, 2014 - Elsevier
MicroRNAs (miRNAs) are a set of non-coding small RNA molecules in control of gene
expression at posttranscriptional/translational level. They not only play crucial roles in …

Malignant pleural mesothelioma: history, controversy, and future of a man-made epidemic

OD Røe, GM Stella - Asbestos and Mesothelioma, 2017 - Springer
Asbestos (Greek, inextinguishable) is the term of a family of naturally occurring minerals that
have been used in small scale since ancient times. Industrialization demanded increased …

Deciphering signaling pathway interplay via miRNAs in malignant pleural mesothelioma

A Salman, SSA Mageed, D Fathi, MA Elrebehy… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly invasive form of lung cancer that
adversely affects the pleural and other linings of the lungs. MPM is a very aggressive tumor …

[HTML][HTML] Tumor suppressor microRNAs contribute to the regulation of PD-L1 expression in malignant pleural mesothelioma

SC Kao, YY Cheng, M Williams, MB Kirschner… - Journal of Thoracic …, 2017 - Elsevier
Introduction The upregulation of programmed death ligand 1 (PD-L1) is found in many
cancers and contributes to evasion of the host's immune defense. In malignant pleural …

MicroRNA profiling in cancer

R Munker, GA Calin - Clinical science, 2011 - portlandpress.com
The diagnosis of cancer has undergone major changes in the last 40 years. Once based
purely on morphology, diagnosis has come to incorporate immunological, cytogenetic and …

[HTML][HTML] Increased circulating miR-625-3p: a potential biomarker for patients with malignant pleural mesothelioma

MB Kirschner, YY Cheng, B Badrian, SC Kao… - Journal of thoracic …, 2012 - Elsevier
Introduction: We investigated the ability of cell-free microRNAs (miRNAs) in plasma and
serum to serve as a biomarker for malignant mesothelioma (MM). Methods: Using miRNA …

[HTML][HTML] New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas

BT Mossman, A Shukla, NH Heintz… - The American journal of …, 2013 - Elsevier
Malignant mesothelioma (MM) is a relatively rare but devastating tumor that is increasing
worldwide. Yet, because of difficulties in early diagnosis and resistance to conventional …

Tumor immune microenvironment and genetic alterations in mesothelioma

S Hiltbrunner, L Mannarino, MB Kirschner… - Frontiers in …, 2021 - frontiersin.org
Malignant pleural mesothelioma (MPM) is a rare and fatal disease of the pleural lining. Up to
80% of the MPM cases are linked to asbestos exposure. Even though its use has been …

Association of MiR-126 with soluble mesothelin-related peptides, a marker for malignant mesothelioma

L Santarelli, E Strafella, S Staffolani, M Amati… - PloS one, 2011 - journals.plos.org
Background Improved detection methods for diagnosis of malignant pleural mesothelioma
(MPM) are essential for early and reliable detection as well as treatment. Since recent data …