Cardiotoxicity of anticancer treatments: epidemiology, detection, and management

G Curigliano, D Cardinale, S Dent… - CA: a cancer journal …, 2016 - Wiley Online Library
Answer questions and earn CME/CNE Cancer and heart disease are the leading causes of
morbidity and mortality in the industrialized world. Modern treatment strategies have led to …

Updates in anthracycline-mediated cardiotoxicity

CG Nebigil, L Désaubry - Frontiers in Pharmacology, 2018 - frontiersin.org
Cardiotoxicity is one of the main adverse effects of chemotheraphy, affecting the completion
of cancer therapies and the short-and long-term quality of life. Anthracyclines are currently …

Genetic variants associated with cancer therapy–induced cardiomyopathy

P Garcia-Pavia, Y Kim, MA Restrepo-Cordoba… - Circulation, 2019 - Am Heart Assoc
Background: Cancer therapy–induced cardiomyopathy (CCM) is associated with cumulative
drug exposures and preexisting cardiovascular disorders. These parameters incompletely …

[HTML][HTML] Anthracycline-induced cardiotoxicity: A multicenter randomised trial comparing two strategies for guiding prevention with enalapril: The International …

D Cardinale, F Ciceri, R Latini, MG Franzosi… - European journal of …, 2018 - Elsevier
Background Troponin changes over time have been suggested to allow for an early
diagnosis of cardiac injury ensuing cancer chemotherapy; cancer patients with troponin …

The role of biomarkers in cardio-oncology

K Ananthan, AR Lyon - Journal of cardiovascular translational research, 2020 - Springer
In the field of cardio-oncology, it is well recognised that despite the benefits of chemotherapy
in treating and possibly curing cancer, it can cause catastrophic damage to bystander …

Cardiotoxic effects of anthracycline-based therapy: what is the evidence and what are the potential harms?

BE Levis, PF Binkley, CL Shapiro - The Lancet Oncology, 2017 - thelancet.com
Despite the known cardiotoxic effects of doxorubicin and other anthracyclines, no evidence-
based guidelines exist for the surveillance and prevention of chemotherapy-induced …

Doxorubicin targets multiple players: a new view of an old problem

D Cappetta, F Rossi, E Piegari, F Quaini… - Pharmacological …, 2018 - Elsevier
Anthracycline cardiotoxicity remains a serious problem in paediatric and adult cancer
survivors, and the advancement of cardio-oncology is a necessary step for an effective care …

Precision cardio-oncology: understanding the cardiotoxicity of cancer therapy

X Han, Y Zhou, W Liu - NPJ precision oncology, 2017 - nature.com
Current oncologic treatments have brought a strong reduction in mortality in cancer patients.
However, the cancer therapy-related cardiovascular complications, in particular chemo …

Efficacy and safety of cardioprotective drugs in chemotherapy-induced cardiotoxicity: an updated systematic review & network meta-analysis

A Mir, Y Badi, S Bugazia, AZ Nourelden, AH Fathallah… - Cardio-Oncology, 2023 - Springer
Background Cancer patients receiving chemotherapy have an increased risk of
cardiovascular complications. This limits the widespread use of lifesaving therapies, often …

Breast cancer therapy-associated cardiovascular disease

TM Zagar, DM Cardinale, LB Marks - Nature reviews Clinical oncology, 2016 - nature.com
Breast cancer treatments have evolved over the past decades, although several widely used
treatments have adverse cardiac effects. Radiotherapy generally improves the survival of …