Introduction to extracellular vesicles: biogenesis, RNA cargo selection, content, release, and uptake
ER Abels, XO Breakefield - Cellular and molecular neurobiology, 2016 - Springer
Extracellular vesicles are a heterogeneous group of membrane-limited vesicles loaded with
various proteins, lipids, and nucleic acids. Release of extracellular vesicles from its cell of …
various proteins, lipids, and nucleic acids. Release of extracellular vesicles from its cell of …
Technical challenges of working with extracellular vesicles
Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …
Detection of neuron-derived pathological α-synuclein in blood
To date, no reliable clinically applicable biomarker has been established for Parkinson's
disease. Our results indicate that a long anticipated blood test for Parkinson's disease may …
disease. Our results indicate that a long anticipated blood test for Parkinson's disease may …
Neuroinflammation and depression: microglia activation, extracellular microvesicles and microRNA dysregulation
D Brites, A Fernandes - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Patients with chronic inflammation are often associated with the emergence of depression
symptoms, while diagnosed depressed patients show increased levels of circulating …
symptoms, while diagnosed depressed patients show increased levels of circulating …
Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases
A Ståhl, K Johansson, M Mossberg, R Kahn… - Pediatric …, 2019 - Springer
Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in
size, including exosomes, microvesicles, and apoptotic bodies. They are released under …
size, including exosomes, microvesicles, and apoptotic bodies. They are released under …
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
Current methods for the isolation of extracellular vesicles
Extracellular vesicles (EVs), including microvesicles and exosomes, are nano-to micron-
sized vesicles, which may deliver bioactive cargos that include lipids, growth factors and …
sized vesicles, which may deliver bioactive cargos that include lipids, growth factors and …
Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90
Antibodies targeting receptor-mediated entry of HCV into hepatocytes confer limited
therapeutic benefits. Evidence suggests that exosomes can transfer genetic materials …
therapeutic benefits. Evidence suggests that exosomes can transfer genetic materials …
Exosomes and cardiac repair after myocardial infarction
S Sahoo, DW Losordo - Circulation research, 2014 - Am Heart Assoc
Myocardial infarction is a leading cause of death among all cardiovascular diseases. The
analysis of molecular mechanisms by which the ischemic myocardium initiates repair and …
analysis of molecular mechanisms by which the ischemic myocardium initiates repair and …
Colorectal cancer-derived small extracellular vesicles establish an inflammatory premetastatic niche in liver metastasis
Y Shao, T Chen, XI Zheng, S Yang, K Xu… - …, 2018 - academic.oup.com
Liver metastases develop in more than half of the patients with colorectal cancer (CRC) and
are associated with a poor prognosis. The factors influencing liver metastasis of CRC are …
are associated with a poor prognosis. The factors influencing liver metastasis of CRC are …