Exploring the impact of co-exposure timing on drug-drug interactions in signal detection through spontaneous reporting system databases: a scoping review

M Cocco, C Carnovale, E Clementi… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Drug-drug interactions (DDIs) are defined as the pharmacological
effects produced by the concomitant administration of two or more drugs. To minimize false …

[HTML][HTML] Discovering clinical drug-drug interactions with known pharmacokinetics mechanisms using spontaneous reporting systems and electronic health records

E Jeong, Y Su, L Li, Y Chen - Journal of Biomedical Informatics, 2024 - Elsevier
Objective Although the mechanisms behind pharmacokinetic (PK) drug-drug interactions
(DDIs) are well-documented, bridging the gap between this knowledge and clinical …

[HTML][HTML] Zileuton

D Bouchette, CV Preuss - 2017 - europepmc.org
Zileuton - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu
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Comment on:" A Disproportionality Analysis of Drug–Drug Interactions of Tizanidine and CYP1A2 Inhibitors from the FDA Adverse Event Reporting System (FAERS)"

Y Noguchi - Drug Safety, 2022 - Springer
Villa-Zapata et al. used case data from the FDA Adverse Event Reporting System (FAERS)
to investigate the occurrence of adverse events reported with the combination of tizanidine …

In silico testing of C9H12ClNO2 and C6H5Cl2NO as derivatives of acetaminophen using molecular docking method

J LORELL, K IVANA, JPW TANOTO… - Notulae Scientia …, 2024 - notulaebiologicae.ro
Paracetamol, a commonly used analgesic and antipyretic medication, is well-known for its
ability to relieve pain and reduce temperature. However, there is a constant push to improve …

Authors' Response to Yoshihiro Noguchi's Comment on:“A Disproportionality Analysis of Drug-Drug Interactions of Tizanidine and CYP1A2 Inhibitors from the FDA …

DC Malone, L Villa-Zapata, A Gómez-Lumbreras… - Drug Safety, 2022 - Springer
The pharmacokinetic interaction of tizanidine with drugs that inhibit the function of CYP1A2
is a serious concern that had been reported in drug product labeling and other publications …

[HTML][HTML] Zafirlukast

A Dhaliwal, T Bajaj - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Zafirlukast - StatPearls - NCBI Bookshelf US flag An official website of the United States
government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …

[PDF][PDF] In silico testing of C9H12ClNO2 and C6H5Cl2NO as derivatives of acetaminophen using acetaminophen using molecular docking method molecular docking …

O TJOA, K ALINA, AA PARIKESIT, F SUTANTO - academia.edu
Paracetamol, a commonly used analgesic and antipyretic medication, is well-known for its
ability to relieve pain and reduce temperature. However, there is a constant push to improve …

Signal Analysis of Drug–Drug Interactions Using Spontaneous Reporting Methods

R Singh, R Sharma, D Pandita, A Kumar - Signal Analysis in … - taylorfrancis.com
Drug-drug interactions (DDIs) pose a significant concern in healthcare, as they can lead to
adverse events, reduced drug efficacy, and compromised patient safety. Spontaneous …

[HTML][HTML] Continuing Education Activity

JS Dhaliwal, A Rosani, A Saadabadi - europepmc.org
Objectives: Identify the indications for using diazepam. Summarize the adverse effects of
diazepam. Review the mechanism of action of diazepam. Outline the importance of …