Pancreatic neuroendocrine neoplasms: 2020 update on pathologic and imaging findings and classification

L Khanna, SR Prasad, A Sunnapwar, S Kondapaneni… - Radiographics, 2020 - pubs.rsna.org
Pancreatic neuroendocrine neoplasms (panNENs) are heterogeneous neoplasms with
neuroendocrine differentiation that show characteristic clinical, histomorphologic, and …

Everolimus in the treatment of neuroendocrine tumors: efficacy, side-effects, resistance, and factors affecting its place in the treatment sequence

L Lee, T Ito, RT Jensen - Expert opinion on pharmacotherapy, 2018 - Taylor & Francis
Introduction: Since the initial approval of everolimus in 2011, there have been a number of
important changes in therapeutic/diagnostic modalities as well as classification/staging …

Therapeutic strategies for patients with neuroendocrine neoplasms: current perspectives

R Modica, A Liccardi, R Minotta… - Expert Review of …, 2022 - Taylor & Francis
ABSTRACT Introduction Neuroendocrine neoplasms (NENs) are a heterogeneous group of
malignancies mainly arising in the gastroenteropancreatic (GEP) and bronchopulmonary …

Image-guided precision medicine in the diagnosis and treatment of pheochromocytomas and paragangliomas

G Gabiache, C Zadro, L Rozenblum, D Vezzosi… - Cancers, 2023 - mdpi.com
Simple Summary Pheochromocytomas and paragangliomas are rare neural-crest-derived
tumors with variable prognosis. In an era of tailored treatment strategies, medical imaging …

mTOR pathway in gastroenteropancreatic neuroendocrine tumor (GEP-NETs)

S Zanini, S Renzi, F Giovinazzo… - Frontiers in …, 2020 - frontiersin.org
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) originate from
neuroendocrine cells in the gastrointestinal tract. They are heterogeneous, and though …

Use of targeted therapeutics in epithelial ovarian cancer: a review of current literature and future directions

MH Vetter, JL Hays - Clinical therapeutics, 2018 - Elsevier
Purpose Epithelial ovarian cancer (EOC) is the leading cause of gynecologic cancer death
in the United States. Most patients will ultimately fail platinum-based chemotherapy and …

Addressing the role of angiogenesis in patients with advanced pancreatic neuroendocrine tumors treated with everolimus: a biological prospective analysis of soluble …

CA Cella, F Spada, A Berruti, F Bertolini, P Mancuso… - Cancers, 2022 - mdpi.com
Simple Summary Despite the approval of new targeted therapies for pancreatic
neuroendocrine tumors (PanNETs) over the past decades, the early identification of resistant …

[HTML][HTML] Update in clinical management for gallbladder neuroendocrine carcinoma

H Chu, Y Shi, J Liu, D Huang, J Zhang, C Dou - Medicine, 2021 - journals.lww.com
Background: Gallbladder neuroendocrine carcinoma (GB-NEC) is rare and there are few
reports at present. We sought to review the current knowledge of GB-NEC and provide …

Predictive factors for resistant disease with Medical/Radiologic/Liver-directed anti-tumor treatments in patients with advanced pancreatic neuroendocrine neoplasms …

L Lee, I Ramos-Alvarez, RT Jensen - Cancers, 2022 - mdpi.com
Simple Summary Tumor resistance, both primary and acquired, is leading to increased
complexity in the nonsurgical treatment of patients with advanced panNENs, which would be …

Molecular signatures and their clinical utility in pancreatic neuroendocrine tumors

PD Chatani, SK Agarwal, SM Sadowski - Frontiers in Endocrinology, 2021 - frontiersin.org
Pancreatic neuroendocrine tumors (PNETs) are classified based on their histologic
differentiation and proliferative indices, which have been used extensively to determine …