Techniques of assessing small airways dysfunction
W McNulty, OS Usmani - European clinical respiratory journal, 2014 - Taylor & Francis
The small airways are defined as those less than 2 mm in diameter. They are a major site of
pathology in many lung diseases, not least chronic obstructive pulmonary disease (COPD) …
pathology in many lung diseases, not least chronic obstructive pulmonary disease (COPD) …
New and current clinical imaging techniques to study chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized
by both small airway and parenchymal abnormalities. There is increasing evidence to …
by both small airway and parenchymal abnormalities. There is increasing evidence to …
Hyperpolarized 3He and 129Xe MR Imaging in Healthy Volunteers and Patients with Chronic Obstructive Pulmonary Disease
Purpose To quantitatively compare hyperpolarized helium 3 (3He) and xenon 129 (129Xe)
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
Hyperpolarized 3He magnetic resonance functional imaging semiautomated segmentation
RATIONALE AND OBJECTIVES: To improve intra-and interobserver variability and enable
the use of functional magnetic resonance imaging (MRI) for multicenter, multiobserver …
the use of functional magnetic resonance imaging (MRI) for multicenter, multiobserver …
Hyperpolarized 3He and 129Xe MRI: Differences in asthma before bronchodilation
S Svenningsen, M Kirby, D Starr… - Journal of magnetic …, 2013 - Wiley Online Library
Purpose To compare hyperpolarized helium‐3 (3He) and xenon‐129 (129Xe) MRI in
asthmatics before and after salbutamol inhalation. Materials and Methods Seven asthmatics …
asthmatics before and after salbutamol inhalation. Materials and Methods Seven asthmatics …
Hyperpolarized 129Xe MR Imaging of Alveolar Gas Uptake in Humans
ZI Cleveland, GP Cofer, G Metz, D Beaver, J Nouls… - PloS one, 2010 - journals.plos.org
Background One of the central physiological functions of the lungs is to transfer inhaled
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
Is computed tomography airway count related to asthma severity and airway structure and function?
Rationale: In patients with asthma, X-ray computed tomography (CT) has provided evidence
of thickened airway walls and airway occlusions, but the total number of CT-visible airways …
of thickened airway walls and airway occlusions, but the total number of CT-visible airways …
What are ventilation defects in asthma?
Background Hyperpolarised 3He MRI provides a way to visualise regional pulmonary
functional abnormalities that in asthma are thought to be related to airway morphological …
functional abnormalities that in asthma are thought to be related to airway morphological …
Hyperpolarized 3He Ventilation Defects Used to Predict Pulmonary Exacerbations in Mild to Moderate Chronic Obstructive Pulmonary Disease
Purpose To evaluate the predictive value of imaging and clinical and physiological
measurements of chronic obstructive pulmonary disease (COPD chronic obstructive …
measurements of chronic obstructive pulmonary disease (COPD chronic obstructive …
Free-breathing Dynamic 19F Gas MR Imaging for Mapping of Regional Lung Ventilation in Patients with COPD
M Gutberlet, TF Kaireit, A Voskrebenzev, F Lasch… - Radiology, 2018 - pubs.rsna.org
Purpose To quantify regional lung ventilation in patients with chronic obstructive pulmonary
disease (COPD) by using free-breathing dynamic fluorinated (fluorine 19 [19F]) gas …
disease (COPD) by using free-breathing dynamic fluorinated (fluorine 19 [19F]) gas …