Oxidative stress (OS) represents a threat to the chemical integrity of biomolecules including
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …

Coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a newly
discovered highly pathogenic virus that was declared pandemic in March 2020 by the World …

Melatonin is a hormone produced by the pineal gland, and it has extensive beneficial effects
on various tissue and organs; however, whether melatonin has any effect on cardiac fibrosis …

Sepsis is a systemic inflammatory response to infection that causes severe neurological
complications. Previous studies have suggested that melatonin is protective during sepsis …

This study investigated the effects of melatonin on diabetic cardiomyopathy (DCM) and
determined the underlying mechanisms. Echocardiography indicated that melatonin notably …

DNA repair is responsible for maintaining the integrity of the genome. Perturbations in the
DNA repair pathways have been identified in several human cancers. Thus, compounds …

Stroke is a fatal cerebral vascular disease with a high mortality rate and substantial
economic and social costs. ROS production and neuroinflammation have been implicated in …

Background Diabetes mellitus (DM) and periodontitis are two common chronic diseases with
bidirectional relationship. Oxidative stress plays a key role in the pathogenesis of these two …

Diabetes and diabetic complications are considered as leading causes of both morbidity
and mortality in the world. Unfortunately, routine medical treatments used for affected …

Diabetes mellitus (DM) and diabetes-related complications are amongst the leading causes
of mortality worldwide. The international diabetes federation (IDF) has estimated 592 million …