The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

Aptamers are short DNA/RNA oligonucleotides capable of binding to target molecules with
high affinity and specificity. The process of selecting an aptamer is called Systematic …

Nanodiagnostics as a field makes use of fundamental advances in nanobiotechnology to
diagnose, characterize and manage disease at the molecular scale. As these strategies …

Aptamers are single-stranded nucleic acids that selectively bind to target molecules. Most
aptamers are obtained through a combinatorial biology technique called SELEX. Since …

Systematic evolution of ligands by exponential enrichment (SELEX) is a well-established
and efficient technology for the generation of oligonucleotides with a high target affinity …

Within the last decade, the application range of aptamers in biochemistry and medicine has
expanded rapidly. More than just a replacement for antibodies, these intrinsically structured …

For many years, different probing techniques have mainly relied on antibodies for molecular
recognition. However, with the discovery of aptamers, this has changed. The science …

The field of micro total analysis systems (μTAS)(1) or lab on a chip (LOC) has extended its
usefulness into many new fields and disciplines spanning basic research to commercial …

Single-stranded oligonucleotide aptamers have attracted great attention in the past decade
because of their diagnostic and therapeutic potential. These versatile, high affinity and …