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Rapidly Progressive Dementia : CONTINUUM: Lifelong Learning in Neurology Account
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Importance Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly lethal disease. Rapid,
accurate diagnosis is imperative for epidemiological surveillance and public health activities …

Human prion diseases are rapidly progressive and fatal neurodegenerative conditions
caused by a disease-causing isoform of the native prion protein. The prion protein gene …

Definitive diagnosis of sporadic Creutzfeldt–Jakob disease (sCJD) relies on the examination
of brain tissues for the pathological prion protein (PrPSc). Our previous study revealed that …

Prion diseases are rapidly progressive, invariably fatal, transmissible neurodegenerative
disorders associated with the accumulation of the amyloidogenic form of the prion protein in …

Prion diseases are difficult to recognize as many symptoms are shared among other
neurologic pathologies and the full spectra of symptoms usually do not appear until late in …

Background Evaluation of the application of CSF real-time quaking-induced conversion in
Creutzfeldt–Jakob disease surveillance to investigate test accuracy, influencing factors, and …

Objective To investigate brain MRI abnormalities in a cohort of patients with rapidly
progressive dementia (RPD) with and without a diagnosis of Creutzfeldt–Jakob disease …

Abstract Introduction Sporadic Creutzfeldt‐Jakob disease (sCJD) comprises multiple
subtypes (MM1, MM2, MV1, MV2C, MV2K, VV1, and VV2) with distinct disease durations …