The widespread use of uranium for civilian purposes causes a worldwide concern of its
threat to human health due to the long-lived radioactivity of uranium and the high toxicity of …

A critical discussion is presented about the possible role of Pt–protein interactions in the
mechanisms of action of platinum anticancer compounds. Although, since 40 years from its …

The combined use of X-ray crystallography and mass spectrometry represents a valuable
strategy to investigate and characterize protein metalation induced by anticancer metal …

Proteins perform their functions in solution but their structures are most frequently studied
inside crystals. Here we probe how the crystal packing alters microsecond dynamics, using …

The large majority of three-dimensional structures of biological macromolecules have been
determined by X-ray diffraction of crystalline samples. High-resolution structure …

Probing the dynamics of aromatic side chains provides important insights into the behavior
of a protein because flips of aromatic rings in a protein's hydrophobic core report on …

Ubiquitination, a post-translational modification that attaches one or more ubiquitin (Ub)
molecules to another protein, plays a crucial role in the phase-separation processes …

Cadmium is an environmental pollutant that constitutes a major danger to human health. It is
considered a definite human carcinogen. The lung and kidney are the most sensitive organs …

Intraneuronal inclusions consisting of hypermetallated,(poly‐) ubiquitinated proteins are a
hallmark of neurodegeneration. To highlight the possible role played by metal ions in the …

As protein crystals are increasingly finding diverse applications as scaffolds, controlled
crystal polymorphism presents a facile strategy to form crystalline assemblies with …