Anti-inflammatory and immunomodulatory effects of probiotics in gut inflammation: a door to the body

F Cristofori, VN Dargenio, C Dargenio… - Frontiers in …, 2021 - frontiersin.org
Hosting millions of microorganisms, the digestive tract is the primary and most important part
of bacterial colonization. On one side, in cases of opportunistic invasion, the abundant …

Zonulin as a potential therapeutic target in microbiota-gut-brain axis disorders: encouraging results and emerging questions

A Veres-Székely, C Szász, D Pap, B Szebeni… - International journal of …, 2023 - mdpi.com
The relationship between dysbiosis and central nervous diseases has been proved in the
last 10 years. Microbial alterations cause increased intestinal permeability, and the …

Interaction between gut microbiota and celiac disease: from pathogenesis to treatment

RE Rossi, G Dispinzieri, A Elvevi, S Massironi - Cells, 2023 - mdpi.com
Celiac disease (CD) is a common systemic disorder that results from an abnormal response
of human immunity to gluten intake, affecting the small intestine. In individuals who carry a …

Effective degradation of gluten and its fragments by gluten-specific peptidases: a review on application for the treatment of patients with gluten sensitivity

YE Dunaevsky, VF Tereshchenkova, MA Belozersky… - Pharmaceutics, 2021 - mdpi.com
To date, there is no effective treatment for celiac disease (CD, gluten enteropathy), an
autoimmune disease caused by gluten-containing food. Celiac patients are supported by a …

Gut microbiota alteration and its modulation with probiotics in celiac disease

A Saviano, C Petruzziello, M Brigida… - Biomedicines, 2023 - mdpi.com
Celiac disease (CD) is a chronic inflammation of the small intestine triggered by gluten
ingestion in genetically predisposed people. Recent literature studies highlight the possible …

Celiac disease and possible dietary interventions: from enzymes and probiotics to postbiotics and viruses

SK Wagh, KM Lammers, MV Padul… - International Journal of …, 2022 - mdpi.com
Celiac Disease (CeD) is a chronic small intestinal immune-mediated enteropathy caused by
the ingestion of dietary gluten proteins in genetically susceptible individuals. CeD is one of …

The tight junction and the epithelial barrier in coeliac disease

A Jauregi-Miguel - International review of cell and molecular biology, 2021 - Elsevier
Epithelial barriers are essential to maintain multicellular organisms well compartmentalized
and protected from external environment. In the intestine, the epithelial layer orchestrates a …

Selection of gut-resistant bacteria and construction of microbial consortia for improving gluten digestion under simulated gastrointestinal conditions

M De Angelis, S Siragusa, M Vacca, R Di Cagno… - Nutrients, 2021 - mdpi.com
This work aimed to define the microbial consortia that are able to digest gluten into non-toxic
and non-immunogenic peptides in the human gastrointestinal tract. Methods: 131 out of 504 …

Advances in understanding the potential therapeutic applications of gut microbiota and probiotic mediated therapies in celiac disease

R Francavilla, F Cristofori, M Vacca… - Expert Review of …, 2020 - Taylor & Francis
ABSTRACT Introduction Celiac Disease (CD) is an autoimmune enteropathy caused by
exposure to gluten in genetically predisposed people. While gluten is the main driving force …

Bacterial-based strategies to hydrolyze gluten peptides and protect intestinal mucosa

F Cristofori, R Francavilla, D Capobianco… - Frontiers in …, 2020 - frontiersin.org
Gluten is a mixture of proteins highly resistant to hydrolysis, resulting in the emergence of
toxic peptides responsible for gluten-related disorders. Currently, a gluten-free diet (GFD) is …