Recent evidence shows that mycobacteria have developed novel and specialized secretion
systems for the transport of extracellular proteins across their hydrophobic, and highly …

Serological antibody detection tests for tuberculosis may offer the potential to improve
diagnosis. Recent meta-analyses have shown that commercially available tests have …

Oil-in-water adjuvants have been shown to improve immune responses against pandemic
influenza vaccines as well as reduce the effective vaccine dose, increasing the number of …

ESX‐5 is one of the five type VII secretion systems found in mycobacteria. These secretion
systems are also known as ESAT‐6‐like secretion systems. Here, we have determined the …

Abstract Key Ags of Mycobacterium tuberculosis initially identified in the context of host
responses in healthy purified protein derivative-positive donors and infected C57BL/6 mice …

One‐third of the world population is estimated to have Mycobacterium tuberculosis infection.
Accurate and timely identification of infected individuals is critical for treatment and control …

The ESX‐1 secretion system plays a critical role in the virulence of Mycobacterium
tuberculosis and M. marinum. To date, three proteins are known to be secreted by ESX‐1 …

Screening of genomic expression libraries from Mycobacterium tuberculosis with sera from
tuberculosis (TB) patients or rabbit antiserum to M. tuberculosis led to the identification of …

The variation in sequence and length in the C-terminal region among members of the
unique PE (Pro-Glu) and PPE (Pro-Pro-Glu) protein families of Mycobacterium tuberculosis …

Improved diagnostic reagents are needed for the detection of Mycobacterium tuberculosis
infections, and the development of a serodiagnostic test would complement presently …