Alkali-amide controlled selective synthesis of 7-azaindole and 7-azaindoline through domino reactions of 2-fluoro-3-methylpyridine and aldehydes
X Xu, M Ou, YE Wang, T Lin, D Xiong, F Xue… - Organic Chemistry …, 2022 - pubs.rsc.org
Azaindoles and azaindolines are important core structures in pharmaceuticals and natural
products, which have found wide applications in the field of medicinal chemistry. In this …
products, which have found wide applications in the field of medicinal chemistry. In this …
Dearomatization–rearomatization strategy for reductive cross-coupling of indoles with ketones in water
N-Alkylation of indoles is one of the important pathways for the construction of various
biologically active indole molecules. Using ketones as N-alkylation reagent for indoles has …
biologically active indole molecules. Using ketones as N-alkylation reagent for indoles has …
Access to C5-alkylated indolines/indoles via Michael-type Friedel–Crafts alkylation using aryl-nitroolefins
A straightforward synthetic route toward C5-alkylated indolines/indoles has been developed.
The strategy is composed of Zn (OTf) 2-catalyzed Friedel–Crafts alkylation of N …
The strategy is composed of Zn (OTf) 2-catalyzed Friedel–Crafts alkylation of N …
A simple oxindole-based colorimetric HSO4¯ sensor: Naked-eye detection and spectroscopic analysis
S Bayindir, F Lafzi - Journal of Photochemistry and Photobiology A …, 2019 - Elsevier
Detection of hydrogen sulfate from an aqueous organic solvent systems medium attracts to
lots of interest because of could be in most environmental and biological systems. In this …
lots of interest because of could be in most environmental and biological systems. In this …
A facile one-pot method to synthesise 2-alkylated indole and 2, 2′-bis (indolyl) methane derivatives using ketones as electrophiles and their anion sensing ability
S Bayindir, N Saracoglu - RSC advances, 2016 - pubs.rsc.org
Indole derivatives are of great importance because of their biological activity and application
in technology. This study explores the synthesis of 2-alkylated indoles derivatives and 2, 2 …
in technology. This study explores the synthesis of 2-alkylated indoles derivatives and 2, 2 …
The synthesis of new oxindoles as analogs of natural product 3,3-bis(indolyl)oxindole and in vitro evaluation of the enzyme activity of G6PD and 6PGD
Natural and synthetic derivatives that contain an indole core are being used in medical
treatments and technological processes. Therefore, the development of new synthetic …
treatments and technological processes. Therefore, the development of new synthetic …
The synthesis of N‐benzoylindoles as inhibitors of rat erythrocyte glucose‐6‐phosphate dehydrogenase and 6‐phosphogluconate dehydrogenase
Abstract Glucose‐6‐phosphate dehydrogenase (G6PD) and 6‐phosphogluconate
dehydrogenase (6PGD) play an important function in various biochemical processes as they …
dehydrogenase (6PGD) play an important function in various biochemical processes as they …
Synthesis of highly N-substituted indole library via conjugate additions of indoline and their synthetic tool potentials
Synthesis of highly N-substituted indole library via conjugate additions of indoline and their
synthetic tool potentials - ScienceDirect Skip to main contentSkip to article Elsevier logo …
synthetic tool potentials - ScienceDirect Skip to main contentSkip to article Elsevier logo …
Potassium hydroxide catalysed intermolecular aza-Michael addition of 3-cyanoindole to aromatic enones
J Yang, T Li, H Zhou, N Li, D Xie, Z Li - Synlett, 2017 - thieme-connect.com
Indole is one of the utmost important heterocycles as it is an essential nucleus of many
pharmaceutical compounds. Its aza-Michael reaction, however, is underdeveloped because …
pharmaceutical compounds. Its aza-Michael reaction, however, is underdeveloped because …
Bifunctional cinchona alkaloid-squaramide-catalyzed highly enantioselective aza-Michael addition of indolines to α, β-unsaturated ketones
AK Ghosh, B Zhou - Tetrahedron letters, 2013 - Elsevier
An enantioselective aza-Michael addition of indolines to α, β-unsaturated ketones was
achieved using a bifunctional cinchona alkaloid-derived chiral squaramide derivative …
achieved using a bifunctional cinchona alkaloid-derived chiral squaramide derivative …