Advanced lung organoids for respiratory system and pulmonary disease modeling

H Joo, S Min, SW Cho - Journal of Tissue Engineering, 2024 - journals.sagepub.com
Amidst the recent coronavirus disease 2019 (COVID-19) pandemic, respiratory system
research has made remarkable progress, particularly focusing on infectious diseases. Lung …

Regeneration of tracheal neotissue in partially decellularized scaffolds

ZH Tan, S Dharmadhikari, L Liu, J Yu… - NPJ Regenerative …, 2023 - nature.com
Extensive tracheal injury or disease can be life-threatening but there is currently no standard
of care. Regenerative medicine offers a potential solution to long-segment tracheal defects …

Multifunctional medical grade resin with enhanced mechanical and antibacterial properties: the effect of copper nano-inclusions in vat polymerization (VPP) additive …

N Vidakis, M Petousis, VM Papadakis… - Journal of Functional …, 2022 - mdpi.com
Vat photopolymerization (VPP) is an additive manufacturing process commonly used in
medical applications. This work aims, for the first time in the literature, to extend and …

Surgical Innovations in Tracheal Reconstruction: A Review on Synthetic Material Fabrication

U Khalid, P Uchikov, B Hristov, K Kraev… - Medicina, 2023 - mdpi.com
Background and Objectives: The aim of this review is to explore the recent surgical
innovations in tracheal reconstruction by evaluating the uses of synthetic material fabrication …

Development and in vitro/in vivo comparative characterization of cryopreserved and decellularized tracheal grafts

E Stocco, S Barbon, M Mammana, D Trojan, A Bianchin… - Cells, 2023 - mdpi.com
Tracheal reconstruction represents a challenge when primary anastomosis is not feasible.
Within this scenario, the study aim was to develop a new pig-derived decellularized trachea …

Successful early neovascularization in composite tracheal grafts

SC Nyirjesy, J Yu, S Dharmadhikari… - … –Head and Neck …, 2023 - Wiley Online Library
Objective Long‐segment tracheal defects require tissue replacement for successful
reconstruction. Rapid revascularization is imperative to maintain graft function. We …

Assessing the Biocompatibility and Regeneration of Electrospun‐Nanofiber Composite Tracheal Grafts

L Kreber, L Liu, S Dharmadhikari, ZH Tan… - The …, 2024 - Wiley Online Library
Objective Composite tracheal grafts (CTG) combining decellularized scaffolds with external
biomaterial support have been shown to support host‐derived neotissue formation. In this …

Current status and future outlook of additive manufacturing technologies for the reconstruction of the trachea

HY Lee, JW Lee - Journal of Functional Biomaterials, 2023 - mdpi.com
Tracheal stenosis and defects occur congenitally and in patients who have undergone
tracheal intubation and tracheostomy due to long-term intensive care. Such issues may also …

Biosubstitutes for dural closure: Unveiling research, application, and future prospects of dura mater alternatives

D Khurana, A Suresh, R Nayak… - Journal of Tissue …, 2024 - journals.sagepub.com
The dura mater, as the crucial outermost protective layer of the meninges, plays a vital role
in safeguarding the underlying brain tissue. Neurosurgeons face significant challenges in …

Pre-epithelialized cryopreserved tracheal allograft for neo-trachea flap engineering

N Zeng, Y Chen, Y Wu, M Zang, RD Largo… - … in Bioengineering and …, 2023 - frontiersin.org
Background: Tracheal reconstruction presents a challenge because of the difficulty in
maintaining the rigidity of the trachea to ensure an open lumen and in achieving an intact …