The liver is the sixth most common site of primary cancer in humans, and generally arises in
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …

The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …

Deciphering the cell-state transitions underlying immune adaptation across time is
fundamental for advancing biology. Empirical in vivo genomic technologies that capture …

Cancer cells can be conceived as “living organisms” interacting with cellular or non‐cellular
components in the host internal environment, not only the local tumor microenvironment but …

Innate lymphoid cells (ILCs) participate in tissue homeostasis, inflammation, and early
immunity against infection. It is unclear how ILCs acquire effector function and whether these …

T cell–directed cancer immunotherapy often fails to generate lasting tumor control.
Harnessing additional effectors of the immune response against tumors may strengthen the …

Breast cancer is the most frequent cancer among women, and metastases in distant organs
are the leading cause of the cancer‐related deaths. While survival of early‐stage breast …

Group 1 innate lymphoid cells (ILCs) comprising circulating natural killer (cNK) cells and
tissue-resident ILC1s are critical for host defense against pathogens and tumors. Despite a …

Innate lymphoid cells (ILCs) are a group of innate lymphocytes that do not express RAG-
dependent rearranged antigen-specific cell surface receptors. ILCs are classified into five …

Simple Summary Liver metastasis remains the major contributor in colorectal cancer-related
death. It has become clear that the unique immune features of liver microenvironment take …