Liver fibrosis is an advanced liver disease condition, which could progress to cirrhosis and
hepatocellular carcinoma. To date, there is no direct approved antifibrotic therapy, and …

Fibrosis, or tissue scarring, develops as a pathological deviation from the physiological
wound healing response and can occur in various organs such as the heart, lung, liver …

Despite the substantial gains in our understanding of NAFLD/NASH over the past 2
decades, there has been some dissatisfaction with the terminology “non‐alcoholic” which …

Liver fibrosis is a reversible wound-healing process aimed at maintaining organ integrity,
and presents as the critical pre-stage of liver cirrhosis, which will eventually progress to …

Liver fibrosis is a wound-healing response generated against an insult to the liver that
causes liver injury. It has the potential to progress into cirrhosis, and if not prevented, it may …

Abstract Background Mesenchymal stem cells (MSCs) are increasingly being applied as a
therapy for liver fibrosis. Exosomes possess similar functions to their parent cells; however …

Liver fibrosis is a common feature of sustained liver injury and represents a major public
health problem worldwide. Fibrosis is an active research field and discoveries in the last …

Background Hepatobiliary disease currently serves as an urgent health issue in public due
to health-modulating factors such as extension of life expectancy, increasingly sedentary …

Background: Liver fibrosis occurs due to chronic liver disease due to multiple
pathophysiological causes. The main causes for this condition are chronic alcohol abuse …

Backgrounds and Aims Activation of hepatic stellate cells (HSCs) is a central driver of
fibrosis. This study aimed to elucidate the role of the deacetylase sirtuin 6 (Sirt6) in HSC …