Targeting pyrimidine metabolism in the era of precision cancer medicine
W Wang, J Cui, H Ma, W Lu, J Huang - Frontiers in oncology, 2021 - frontiersin.org
Metabolic rewiring is considered as a primary feature of cancer. Malignant cells reprogram
metabolism pathway in response to various intrinsic and extrinsic drawback to fuel cell …
metabolism pathway in response to various intrinsic and extrinsic drawback to fuel cell …
Biosynthesis of GlcNAc-rich N-and O-glycans in the Golgi apparatus does not require the nucleotide sugar transporter SLC35A3
B Szulc, P Sosicka, D Maszczak-Seneczko… - Journal of Biological …, 2020 - ASBMB
Nucleotide sugar transporters, encoded by the SLC35 gene family, deliver nucleotide
sugars throughout the cell for various glycosyltransferase-catalyzed glycosylation reactions …
sugars throughout the cell for various glycosyltransferase-catalyzed glycosylation reactions …
O‐GlcNAcylation regulates β1,4‐GlcNAc‐branched N‐glycan biosynthesis via the OGT/SLC35A3/GnT‐IV axis
W Song, T Isaji, M Nakano, C Liang… - The FASEB …, 2022 - Wiley Online Library
N‐Linked glycosylation and O‐linked N‐acetylglucosamine (O‐GlcNAc) are important
protein post‐translational modifications that are orchestrated by a diverse set of gene …
protein post‐translational modifications that are orchestrated by a diverse set of gene …
Characterization of a gene cluster involved in Aspergillus fumigatus zwitterionic glycosphingolipid synthesis
CII Seegers, I Ramón Roth, P Zarnovican… - …, 2022 - academic.oup.com
The human pathogenic fungus Aspergillus fumigatus synthesizes the zwitterionic glycolipid
Manα1, 3Manα1, 6GlcNα1, 2IPC, named Af3c. Similar glycosphingolipids having a …
Manα1, 3Manα1, 6GlcNα1, 2IPC, named Af3c. Similar glycosphingolipids having a …
Mice lacking nucleotide sugar transporter SLC35A3 exhibit lethal chondrodysplasia with vertebral anomalies and impaired glycosaminoglycan biosynthesis
S Saito, S Mizumoto, T Yonekura, R Yamashita… - Plos one, 2023 - journals.plos.org
SLC35A3 is considered an uridine diphosphate N-acetylglucosamine (UDP-GlcNAc)
transporter in mammals and regulates the branching of N-glycans. A missense mutation in …
transporter in mammals and regulates the branching of N-glycans. A missense mutation in …
A three-pocket model for substrate coordination and selectivity by the nucleotide sugar transporters SLC35A1 and SLC35A2
D Li, S Mukhopadhyay - Journal of Biological Chemistry, 2021 - ASBMB
The CMP-sialic acid transporter SLC35A1 and UDP-galactose transporter SLC35A2 are two
well-characterized nucleotide sugar transporters with distinctive substrate specificities …
well-characterized nucleotide sugar transporters with distinctive substrate specificities …
[HTML][HTML] Transcriptome characterization of Pocillopora grandis transplanted into reefs with different health conditions: potential stress indicators at the holobiont level
OE Juárez, B Morales-Guerrero… - Latin american journal …, 2024 - SciELO Chile
Understanding the potential of coral to adapt to environmental stressors that cause coral
bleaching is urgent. The molecular responses of the coral holobiont to such stress …
bleaching is urgent. The molecular responses of the coral holobiont to such stress …
The broad range di-and tri-nucleotide exchanger SLC35B1 displays asymmetrical affinities for ATP transport across the ER membrane
PJ Schwarzbaum, J Schachter, LM Bredeston - Journal of Biological …, 2022 - ASBMB
In eukaryotic cells, uptake of cytosolic ATP into the endoplasmic reticulum (ER) lumen is
critical for the proper functioning of chaperone proteins. The human transport protein …
critical for the proper functioning of chaperone proteins. The human transport protein …