Epithelial cell adhesion molecule EpCAM is expressed on a subset of normal epithelia and
overexpressed on malignant cells from a variety of different tumor entities. This …

Chimeric antigen receptor (CAR) T cell immunotherapy involves the genetic modification of
the patient's own T cells so that they specifically recognize and destroy tumour cells …

Prostate cancer (CaP) is the second leading malignancy in men. The role of epithelial cell
adhesion molecule (EpCAM), also known as CD326, in CaP progression and therapeutic …

Epithelial cell adhesion molecule (EpCAM) is known to be highly expressed in a variety of
epithelial carcinomas, and it is involved in cell adhesion and proliferation. However, its …

Exosome is a recently emerging cancer-associated biomarker for early diagnostic and
prognostic owing to their noninvasive, intrinsic stability, and representativeness of primitive …

Background: Expression of epithelial cell adhesion molecule (EpCAM) is deregulated in
epithelial malignancies. Beside its role in cell adhesion, EpCAM acts as signalling molecule …

Chemotherapy is one of the most widely used approaches in combating advanced prostate
cancer, but its therapeutic efficacy is usually insufficient due to poor specificity and …

Prostate cancer (PCa) is a leading cause of cancer death in men, worldwide. Mortality is
highly related to metastasis and hormone resistance, but the molecular underlying …

Cholangiocarcinoma (CCA) is the second most common type of liver cancer, and is highly
aggressive with very poor prognosis. CCA is classified into intrahepatic cholangiocarcinoma …

The cell surface protein Trop2 is overexpressed in a variety of human cancers. Trop2
expression increases tumor development and metastasis and reduces patient survival …