Reperfusion injury is associated with poor outcome in patients with recanalization after thrombectomy

Y Zhou, Y He, S Yan, L Chen, R Zhang, J Xu, H Hu… - Stroke, 2023 - Am Heart Assoc
Background: The existence of cerebral reperfusion injury in human beings remains
controversial. Thus, we aimed to explore the presence of reperfusion injury in acute …

The ischemic penumbra: From concept to reality

CM Ermine, A Bivard, MW Parsons… - International Journal of …, 2021 - journals.sagepub.com
The discovery that brain tissue could potentially be salvaged from ischaemia due to stroke,
has led to major advances in the development of therapies for ischemic stroke. In this …

Predicting infarct core from computed tomography perfusion in acute ischemia with machine learning: Lessons from the ISLES challenge

A Hakim, S Christensen, S Winzeck, MG Lansberg… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: The ISLES challenge (Ischemic Stroke Lesion Segmentation)
enables globally diverse teams to compete to develop advanced tools for stroke lesion …

Mechanical thrombectomy in ischemic stroke patients with alberta stroke program early computed tomography score 0–5

J Kaesmacher, P Chaloulos-Iakovidis, L Panos… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—If anterior circulation large vessel occlusion acute ischemic
stroke patients presenting with ASPECTS 0–5 (Alberta Stroke Program Early CT Score) …

A benchmarking tool to evaluate computer tomography perfusion infarct core predictions against a DWI standard

CW Cereda, S Christensen… - Journal of Cerebral …, 2016 - journals.sagepub.com
Differences in research methodology have hampered the optimization of Computer
Tomography Perfusion (CTP) for identification of the ischemic core. We aim to optimize CTP …

Ischemia-reperfusion injury after endovascular thrombectomy for ischemic stroke

M Gauberti, B Lapergue, S Martinez de Lizarrondo… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—In experimental models of ischemic stroke, abrupt reperfusion is
associated with secondary brain damages, responsible for up to 70% of the final lesion size …

Acute stroke with large ischemic core treated by thrombectomy: predictors of good outcome and mortality

P Panni, B Gory, Y Xie, A Consoli, JP Desilles… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Acute stroke patients with a large ischemic core may still benefit
from mechanical thrombectomy (MT), but the predictors of clinical outcome are not well …

[HTML][HTML] Optimizing the definitions of stroke, transient ischemic attack, and infarction for research and application in clinical practice

AL Abbott, M Silvestrini, R Topakian, J Golledge… - Frontiers in …, 2017 - frontiersin.org
Background and purpose Until now, stroke and transient ischemic attack (TIA) have been
clinically based terms which describe the presence and duration of characteristic …

ASPECTS (Alberta Stroke Program Early CT Score) measurement using Hounsfield unit values when selecting patients for stroke thrombectomy

M Mokin, CT Primiani, AH Siddiqui, AS Turk - Stroke, 2017 - Am Heart Assoc
Background and Purpose—The ASPECTS (Alberta Stroke Program Early CT Score) is a
quantitate score that measures the extent of early ischemic changes. Our aim was to …

Reversible diffusion-weighted imaging lesions in acute ischemic stroke: a systematic review

N Nagaraja, JR Forder, S Warach, JG Merino - Neurology, 2020 - AAN Enterprises
Objectives To systematically review the literature for reversible diffusion-weighted imaging
(DWIR) lesions and to describe its prevalence, predictors, and clinical significance. Methods …