Low-grade inflammation is a characteristic of the obese state, and adipose tissue releases
many inflammatory mediators. The source of these mediators within adipose tissue is not …

Mechanisms of Glucocorticoid-Induced Insulin Resistance - Endocrinology and Metabolism
Clinics Skip to Main Content Skip to Main Menu Advertisement Endocrinology and …

Skeletal muscle and adipose tissue are the two largest organs in the body. Skeletal muscle
is an effector organ, and adipose tissue is an organ that stores energy; in addition, they are …

Central obesity is associated with insulin resistance and dyslipidemia. Thus, the
mechanisms that control fat distribution and its impact on systemic metabolism have …

We discuss the anatomy, physiology, and pathophysiology of epicardial adipose tissue and
its relationship to coronary atherosclerosis. Epicardial fat stores triglyceride to supply free …

OBJECTIVE Insulin resistance and other features of the metabolic syndrome have been
causally linked to adipose tissue macrophages (ATMs) in mice with diet-induced obesity. We …

Central (visceral) obesity is more closely associated with insulin resistance, type 2 diabetes,
and cardiovascular disease than is peripheral [subcutaneous (sc)] obesity, but the …

The white adipose tissue, especially of humans, is now recognized as the central player in
the mild inflammatory state that is characteristic of obesity. The question is how the …

Background: Chemotactic cytokines, referred to as chemokines, play an important role in
leukocyte trafficking. The circulating levels of chemokines have been shown to increase in …

Chronic inflammation of adipose tissue in obesity is by now an established phenomenon,
but the initiating event (s) of the inflammatory cascade are still unknown. We hypothesized …