Sleep disturbance is a prevalent and disabling comorbidity in Parkinson's disease (PD). We
performed multi-night (n= 57) at-home intracranial recordings from electrocorticography and …

Brain rhythms can facilitate neural communication for the maintenance of brain function.
Beta rhythms (13–35 Hz) have been proposed to serve multiple domains of human ability …

The globus pallidus plays a pivotal role in the basal ganglia circuit. Parkinson's disease is
characterized by degeneration of dopamine-producing cells in the substantia nigra, which …

Sleep disorders represent prevalent non-motor symptoms in Parkinson's disease (PD),
affecting over 90% of the PD population. Insomnia, characterized by difficulties in initiating …

Circadian rhythms have been shown in the subthalamic nucleus (STN) in Parkinson's
disease (PD), but only a few studies have focused on the globus pallidus internus (GPi). This …

Sleep disturbances profoundly affect the quality of life in individuals with neurological
disorders. Closed-loop deep brain stimulation (DBS) holds promise for alleviating sleep …

Background Deep brain stimulation is a treatment for advanced Parkinson's disease and
currently tuned to target motor symptoms during daytime. Parkinson's disease is associated …

Increasing evidence suggests slow-wave sleep (SWS) dysfunction in Parkinson's disease
(PD) is associated with faster disease progression, cognitive impairment, and excessive …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by dopaminergic
neuron loss, leading to motor and non‐motor symptoms. Early detection before symptom …

Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective
therapy in ameliorating the motor symptoms of Parkinson's disease (PD). However …