Background: Among the millions of people around the world, the most prevalent metabolic
disorder is diabetes mellitus. Due to the drawbacks which are associated with commercially …

Benzimidazole is a nitrogen-containing fused heterocycle which has been extensively
explored in medicinal chemistry. Benzimidizole nucleus has been found to possess various …

Synthetic routes to a series of benzoylarylbenzimidazol 3a-h have been derived from 3, 4-
diaminobenzophenone and an appropriate arylaldehyde in the presence of ammonium …

In the present study, a quantitative relationship between the biological inhibitory activity of
alpha-amylase and molecular structures of novel benzimidazole derivatives is analyzed in …

In our quest to design and develop N/O-containing inhibitors of α-amylase, we have tried to
synergize the inhibitory action of 1, 4-naphthoquinone, imidazole and 1, 2, 3-triazole motifs …

Abstract Some novel benzimidazole‐tethered 1, 2, 3‐triazole derivatives (4a–r) were
synthesized by a click reaction between 2‐substituted 1‐(prop‐2‐yn‐1‐yl)‐1H‐benzo [d] …

Currently, the synthesis of new compounds with potential bioactivities has become a central
issue in the drug discovery arena. Among these new compounds, benzimidazole‐sulfonyl …

Current study is based on the sequential conversion of indolyl butanoic acid (1) into ethyl
indolyl butanoate (2), indolyl butanohydrazide (3), and 1, 3, 4-oxadiazole-2-thiol analogs (4) …

Acarbose and voglibose are well-known α-amylase inhibitors used for the management of
type-II diabetes mellitus. Unfortunately, these well-known and clinically used inhibitors are …

A novel series of acridine linked to thioacetamides 9a–o were synthesized and evaluated for
their α-glucosidase inhibitory and cytotoxic activities. All the synthesized compounds …