Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …

Mammalian adipose tissue can be divided into two major types, namely, white adipose
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …

The ability to efficiently adapt metabolism by substrate sensing, trafficking, storage, and
utilization, dependent on availability and requirement, is known as metabolic flexibility. In …

This review proposes that physical inactivity could be considered a behavior selected by
evolution for resting, and also selected to be reinforcing in life-threatening situations in …

Obesity, which is a worldwide epidemic, confers increased risk for multiple serious
conditions including type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular …

Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

Obesity is associated with chronic inflammation, which contributes to insulin resistance and
type 2 diabetes mellitus. Under normal conditions, skeletal muscle is responsible for the …

White adipose tissue (WAT) is an endocrine organ highly integrated in homeostasis and
capable of establishing ways of communicating and influencing multiple metabolic …

Adipose, skeletal, and hepatic muscle tissues are the main endocrine organs that produce
adipokines, myokines, and hepatokines. These biomarkers can be harmful or beneficial to …

The obesity epidemic shows no signs of abatement. Genetics and overnutrition together with
a dramatic decline in physical activity are the alleged main causes for this pandemic. While …