Breakthroughs in hepatitis C research: from discovery to cure

MP Manns, B Maasoumy - Nature reviews Gastroenterology & …, 2022 - nature.com
In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

N Fujiwara, SL Friedman, N Goossens, Y Hoshida - Journal of hepatology, 2018 - Elsevier
Patients who develop chronic fibrotic liver disease, caused by viral or metabolic aetiologies,
are at a high risk of developing hepatocellular carcinoma (HCC). Even after complete HCC …

The micro-elimination approach to eliminating hepatitis C: strategic and operational considerations

JV Lazarus, K Safreed-Harmon… - Seminars in liver …, 2018 - thieme-connect.com
The introduction of efficacious new hepatitis C virus (HCV) treatments galvanized the World
Health Organization to define ambitious targets for eliminating HCV as a public health threat …

Systematic review: cost‐effectiveness of direct‐acting antivirals for treatment of hepatitis C genotypes 2‐6

T He, MA Lopez‐Olivo, C Hur… - Alimentary …, 2017 - Wiley Online Library
Background The availability of direct‐acting antivirals (DAA s) has dramatically changed the
landscape of hepatitis C virus (HCV) therapy; however, the cost and budget requirements for …

[HTML][HTML] The impact of direct-acting antiviral agents on liver and kidney transplant costs and outcomes

DA Axelrod, MA Schnitzler, T Alhamad… - American journal of …, 2018 - Elsevier
Direct-acting antiviral medications (DAAs) have revolutionized care for hepatitis C positive
(HCV+) liver (LT) and kidney (KT) transplant recipients. Scientific Registry of Transplant …

Transplanting hepatitis C virus–positive livers into hepatitis C virus–negative patients with preemptive antiviral treatment: A modeling study

J Chhatwal, S Samur, ED Bethea, T Ayer, F Kanwal… - Hepatology, 2018 - journals.lww.com
Alcoholic liver disease (ALD) is associated with changes in the intestinal microbiota.
Functional consequences of alcohol‐associated dysbiosis are largely unknown. The aim of …

Liver and kidney recipient selection of hepatitis C virus viremic donors: meeting consensus report from the 2019 controversies in transplantation

JR Burton Jr, NA Terrault, DS Goldberg… - …, 2020 - journals.lww.com
The development of multiple highly effective and safe direct-acting antivirals to treat hepatitis
C virus (HCV) has resulted in greater ease and confidence in managing HCV infection in …

Cost effectiveness of transplanting HCV-infected livers into uninfected recipients with preemptive antiviral therapy

ED Bethea, S Samur, F Kanwal, T Ayer, C Hur… - Clinical …, 2019 - Elsevier
Background & Aims Guidelines do not recommend transplanting hepatitis C virus (HCV)-
infected livers into HCV-uninfected recipients. Direct-acting antivirals (DAAs) can be used to …

[HTML][HTML] Economic evaluation of the hepatitis C elimination strategy in Greece in the era of affordable direct-acting antivirals

I Gountas, V Sypsa, G Papatheodoridis… - World Journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Hepatitis C virus (HCV) is a leading cause of worldwide liver-related
morbidity and mortality. The World Health Organization released an integrated strategy …

Changes in practice and perception of hepatitis C and liver transplantation: results of a national survey

AA Shaffer, AG Thomas, MG Bowring… - Transplant Infectious …, 2018 - Wiley Online Library
With new practice guidelines, it is important to understand how liver transplant (LT) centers
have incorporated direct‐acting antivirals (DAAs) into the management of hepatitis C virus …