Cancer is a complex disease in which several molecular and cellular pathways converge to
foster the tumoral phenotype. Notably, in the latest iteration of the cancer hallmarks,“ …

Donor stem cell health may be critically important to the success of hematopoietic stem cell
transplantation (HSCT). Herein, we performed this systematic review and meta-analysis …

The myelodysplastic syndromes (MDS) constitute a profoundly heterogeneous myeloid
malignancy with a common origin in the hemopoietic stem cell compartment. Consequently …

Aging is a multifaceted process characterized by a gradual decline in physiological function
and increased susceptibility to a range of chronic diseases. Among the molecular and …

Background: Risk factors including smoking, alcohol intake, physical activity (PA), and sleep
patterns have been associated with cancer risk. Clonal hematopoiesis (CH), including …

This viewpoint summarizes findings from analyses of large personal patient databases of
myeloproliferative neoplasms (MPNs) to assess the impact of thrombosis on mortality …

Secondary acute myeloid leukemia (sAML) presents as a complex and multifaceted
ensemble of disorders, positioning itself as both a challenge and an intriguing frontier within …

James German's work to establish the natural history and cancer risk associated with Bloom
syndrome (BS) has had a strong influence on the generation of scientists and clinicians …

Myelodysplastic syndrome (MDS) is a very heterogeneous clonal disorder. Patients with
“higher-risk” MDS, defined by specific recurrent genetic abnormalities, have a poor …

Clonal hematopoiesis of indeterminate potential (CHIP) in patients with chronic lymphocytic
leukemia (CLL) has not been extensively characterized. The objective of this study was to …