Purpose The aim of this study was to analyze the clinical results provided by multi-layer cell-
free scaffolds for the treatment of knee osteochondral defects. Methods A systematic review …

Many patients, particularly those aged above 40, experience knee joint pain, which hampers
both sports activities and daily living. Treating isolated chondral and osteochondral defects …

Background: Lesions of the articular cartilage, with or without involvement of the
subchondral bone, are a common cause of pain and dysfunction in the knee. Although …

Regeneration of hyaline cartilage in human-sized joints remains a clinical challenge, and it
is a critical unmet need that would contribute to longer healthspans. Injectable scaffolds for …

The treatment of osteochondral joint lesions requires the regeneration of both articular
cartilage and subchondral bone tissue. Scaffold-based strategies aimed at mimicking the …

Objective To develop patient-focused consensus guidelines on the indications for the use of
scaffolds to address chondral and osteochondral femoral condyle lesions. Design The …

Background: Cell-free devices have been introduced to restore osteochondral defects,
avoiding the limitations of cell-based procedures. Among these, an osteochondral scaffold …

Purpose Patellar cartilage lesions are a frequent and challenging finding in orthopaedic
clinical practice. This study aimed to evaluate a chitosan‐based scaffold's mid‐term clinical …

Current surgical techniques to treat articular cartilage defects fail to produce a satisfactory
long-term repair of the tissue. Regenerative approaches show promise in their ability to …

Purpose The aim of this study was to assess how physicians perceive the role of the
reimbursement system and its potential influence in affecting their treatment choice in the …