Pemphigus represents a group of rare and severe autoimmune intra-epidermal blistering
diseases affecting the skin and mucous membranes. These painful and debilitating diseases …

Pemphigus represents a group of chronic inflammatory disorders characterized by
autoantibodies that target components of desmosomes, leading to the loss of intercellular …

Pemphigus is a group of autoimmune bullous skin diseases that result in significant
morbidity. As for other multifactorial autoimmune disorders, environmental factors may …

Background Pemphigus vulgaris (PV) is an autoimmune bullous disease mediated by
autoantibodies against desmoglein 3 (DSG3). Inducible costimulator (ICOS) is a …

Blockade of immune checkpoints transformed the paradigm of systemic cancer therapy,
enabling substitution of a cytotoxic chemotherapy backbone to one of immunostimulation in …

Pemphigus foliaceus (PF) is an autoimmune blistering disease of the skin, clinically
characterized by erosions and, histopathologically, by acantholysis. PF is endemic in the …

Co-stimulatory molecules are essential in the orchestration of immune response and
polymorphisms in their genes are associated with various diseases. However, in the case of …

Background Pemphigus foliaceus (PF) is an epidermal autoimmune disease, characterized
by the presence of autoantibodies against the desmosomal protein desmoglein 1. Genetic …

Pemphigus foliaceus (PF) is a blistering autoimmune skin disease rare in most of the world
but endemic in certain regions of Brazil. PF is characterized by the detachment of epidermal …

Skin blisters of pemphigus foliaceus (PF) present concomitant deposition of autoantibodies
and components of the complement system (CS), whose gene polymorphisms are …