Exploring the use of animal models in craniofacial regenerative medicine: a narrative review

SA Mosaddad, A Hussain… - Tissue Engineering Part B …, 2024 - liebertpub.com
The craniofacial region contains skin, bones, cartilage, the temporomandibular joint (TMJ),
teeth, periodontal tissues, mucosa, salivary glands, muscles, nerves, and blood vessels …

Advancements in regenerative strategies through the continuum of burn care

R Stone II, S Natesan, CJ Kowalczewski… - Frontiers in …, 2018 - frontiersin.org
Burns are caused by several mechanisms including flame, scald, chemical, electrical, and
ionizing and non-ionizing radiation. Approximately half a million burn cases are registered …

Accelerated wound closure of deep partial thickness burns with acellular fish skin graft

R Stone, EC Saathoff, DA Larson, JT Wall… - International Journal of …, 2021 - mdpi.com
Thermal injuries are caused by exposure to a variety of sources, and split thickness skin
grafts are the gold standard treatment for severe burns; however, they may be impossible …

[HTML][HTML] Inflammation as an orchestrator of cutaneous scar formation: A review of the literature

TA Wilgus - Plastic and aesthetic research, 2020 - ncbi.nlm.nih.gov
Inflammation is a key phase in the cutaneous wound repair process. The activation of
inflammatory cells is critical for preventing infection in contaminated wounds and results in …

In Vitro, Ex Vivo, and In Vivo Approaches for Investigation of Skin Scarring: Human and Animal Models

LMG Neves, TA Wilgus, A Bayat - Advances in Wound Care, 2023 - liebertpub.com
Significance: The cutaneous repair process naturally results in different types of scarring that
are classified as normal or pathological. Affected individuals are often affected from an …

Effect of skin graft thickness on scar development in a porcine burn model

DM DeBruler, BN Blackstone, KL McFarland… - Burns, 2018 - Elsevier
Animal models provide a way to investigate scar therapies in a controlled environment. It is
necessary to produce uniform, reproducible scars with high anatomic and biologic similarity …

The pig as a model system for investigating the recruitment and contribution of myofibroblasts in skin healing

DW Hamilton, JT Walker, D Tinney… - Wound Repair and …, 2022 - Wiley Online Library
In the skin‐healing field, porcine models are regarded as a useful analogue for human skin
due to their numerous anatomical and physiological similarities. Despite the widespread use …

Spatial frequency domain imaging: a quantitative, noninvasive tool for in vivo monitoring of burn wound and skin graft healing

GT Kennedy, R Stone… - … of biomedical optics, 2019 - spiedigitallibrary.org
There is a need for noninvasive, quantitative methods to characterize wound healing in the
context of longitudinal investigations related to regenerative medicine. Such tools have the …

Coming to consensus: what defines deep partial thickness burn injuries in porcine models?

ALF Gibson, BC Carney, L Cuttle… - Journal of Burn Care …, 2021 - academic.oup.com
Deep partial thickness burns are clinically prevalent and difficult to diagnose. In order to
develop methods to assess burn depth and therapies to treat deep partial thickness burns …

Lipid mediator profiles of burn wound healing: Acellular cod fish skin grafts promote the formation of EPA and DHA derived lipid mediators following seven days of …

A Kotronoulas, ALG de Lomana, ST Karvelsson… - … and Essential Fatty …, 2021 - Elsevier
The use of acellular fish skin grafts (FSG) for the treatment of burn wounds is becoming more
common due to its beneficial wound healing properties. In our previous study we …