Approaches for breaking the barriers of drug permeation through transdermal drug delivery
Transdermal drug delivery system (TDDS) utilizes the skin as executable route for drug
administration but the foremost barrier against drug permeability is the stratum corneum and …
administration but the foremost barrier against drug permeability is the stratum corneum and …
Skin permeabilization for transdermal drug delivery: recent advances and future prospects
CM Schoellhammer, D Blankschtein… - Expert opinion on drug …, 2014 - Taylor & Francis
Introduction: Transdermal delivery has potential advantages over other routes of
administration. It could reduce first-pass metabolism associated with oral delivery and is less …
administration. It could reduce first-pass metabolism associated with oral delivery and is less …
Non-invasive drug delivery technology: Development and current status of transdermal drug delivery devices, techniques and biomedical applications
Pay-load deliveries across the skin barrier to the systemic circulation have been one of the
most challenging delivery options. Necessitated requirements of the skin and facilitated skin …
most challenging delivery options. Necessitated requirements of the skin and facilitated skin …
Microneedles for intradermal and transdermal drug delivery
TM Tuan-Mahmood, MTC McCrudden… - European Journal of …, 2013 - Elsevier
The formidable barrier properties of the uppermost layer of the skin, the stratum corneum,
impose significant limitations for successful systemic delivery of broad range of therapeutic …
impose significant limitations for successful systemic delivery of broad range of therapeutic …
Microneedles: an emerging transdermal drug delivery system
Objectives One of the thrust areas in drug delivery research is transdermal drug delivery
systems (TDDS) due to their characteristic advantages over oral and parenteral drug …
systems (TDDS) due to their characteristic advantages over oral and parenteral drug …
Ultrasound mediated transdermal drug delivery
Transdermal drug delivery offers an attractive alternative to the conventional drug delivery
methods of oral administration and injections. However, the stratum corneum serves as a …
methods of oral administration and injections. However, the stratum corneum serves as a …
Micro electromechanical systems (MEMS) based microfluidic devices for biomedical applications
Micro Electromechanical Systems (MEMS) based microfluidic devices have gained
popularity in biomedicine field over the last few years. In this paper, a comprehensive …
popularity in biomedicine field over the last few years. In this paper, a comprehensive …
Microfluidic trends in drug screening and drug delivery
The low probability of a drug candidate's clinical success, the time consumed and the high
cost of bringing a drug from concept to market emphasizes the need for new approaches to …
cost of bringing a drug from concept to market emphasizes the need for new approaches to …
Microneedle mediated transdermal delivery of protein, peptide and antibody based therapeutics: current status and future considerations
M Kirkby, ARJ Hutton, RF Donnelly - Pharmaceutical research, 2020 - Springer
The success of protein, peptide and antibody based therapies is evident-the
biopharmaceuticals market is predicted to reach $388 billion by 2024 [1], and more than half …
biopharmaceuticals market is predicted to reach $388 billion by 2024 [1], and more than half …
Recent advances in microneedle-based drug delivery: Special emphasis on its use in paediatric population
Transdermal drug delivery offers several attractive advantages over the traditional oral and
parenteral routes. Particularly, in case of paediatric patients, it helps to overcome the issues …
parenteral routes. Particularly, in case of paediatric patients, it helps to overcome the issues …