Structural symmetry in membrane proteins
LR Forrest - Annual review of biophysics, 2015 - annualreviews.org
Symmetry is a common feature among natural systems, including protein structures. A strong
propensity toward symmetric architectures has long been recognized for water-soluble …
propensity toward symmetric architectures has long been recognized for water-soluble …
A vocabulary of ancient peptides at the origin of folded proteins
The seemingly limitless diversity of proteins in nature arose from only a few thousand
domain prototypes, but the origin of these themselves has remained unclear. We are …
domain prototypes, but the origin of these themselves has remained unclear. We are …
Internal symmetry in protein structures: prevalence, functional relevance and evolution
S Balaji - Current opinion in structural biology, 2015 - Elsevier
Highlights•About 20% of SCOP folds, superfamilies and families have internal symmetry.•All-
β and membrane folds and superfamilies are the most prominent in symmetry.•Connecting …
β and membrane folds and superfamilies are the most prominent in symmetry.•Connecting …
[HTML][HTML] Automated evaluation of quaternary structures from protein crystals
A correct assessment of the quaternary structure of proteins is a fundamental prerequisite to
understanding their function, physico-chemical properties and mode of interaction with other …
understanding their function, physico-chemical properties and mode of interaction with other …
Stonefish toxin defines an ancient branch of the perforin-like superfamily
The lethal factor in stonefish venom is stonustoxin (SNTX), a heterodimeric cytolytic protein
that induces cardiovascular collapse in humans and native predators. Here, using X-ray …
that induces cardiovascular collapse in humans and native predators. Here, using X-ray …
[HTML][HTML] Repeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanisms
A Vergara-Jaque, C Fenollar-Ferrer… - Frontiers in …, 2015 - frontiersin.org
Secondary active transporters are critical for neurotransmitter clearance and recycling
during synaptic transmission and uptake of nutrients. These proteins mediate the movement …
during synaptic transmission and uptake of nutrients. These proteins mediate the movement …
[HTML][HTML] Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm
Many proteins fold into highly regular and repetitive three dimensional structures. The
analysis of structural patterns and repeated elements is fundamental to understand protein …
analysis of structural patterns and repeated elements is fundamental to understand protein …
[HTML][HTML] H2A-H2B histone dimer plasticity and its functional implications
The protein core of the nucleosome is composed of an H3-H4 histone tetramer and two H2A-
H2B histone dimers. The tetramer organizes the central 60 DNA bp, while H2A-H2B dimers …
H2B histone dimers. The tetramer organizes the central 60 DNA bp, while H2A-H2B dimers …
General principles of secondary active transporter function
O Beckstein, F Naughton - Biophysics Reviews, 2022 - pubs.aip.org
Transport of ions and small molecules across the cell membrane against electrochemical
gradients is catalyzed by integral membrane proteins that use a source of free energy to …
gradients is catalyzed by integral membrane proteins that use a source of free energy to …
Analytical symmetry detection in protein assemblies. I. Cyclic symmetries
Symmetry in protein, and, more generally, in macromolecular assemblies is a key point to
understand their structure, stability and function. Many symmetrical assemblies are currently …
understand their structure, stability and function. Many symmetrical assemblies are currently …