The control of body and organ growth is essential for the development of adults with proper
size and proportions, which is important for survival and reproduction. In animals, adult body …

Organisms adapt to changing environments by adjusting their development, metabolism,
and behavior to improve their chances of survival and reproduction. To achieve such …

The Drosophila wing imaginal disc is a tissue of undifferentiated cells that are precursors of
the wing and most of the notum of the adult fly. The wing disc first forms during …

Many male animals wield ornaments or weapons of exaggerated proportions. We propose
that increased cellular sensitivity to signaling through the insulin/insulin-like growth factor …

Morphological allometry refers to patterns of covariance between body parts resulting from
variation in body size. Whether measured during growth (ontogenetic allometry), among …

Morphological traits often covary within and among species according to simple power laws
referred to as allometry. Such allometric relationships may result from common growth …

Physiology and metabolism are often sexually dimorphic, but the underlying mechanisms
remain incompletely understood. Here, we use the intestine of Drosophila melanogaster to …

Over the past two decades, fundamental strides in physiology and genetics have allowed us
to finally grasp the developmental mechanisms regulating body size, primarily in one model …

Organisms from slime moulds to humans carefully regulate their macronutrient intake to
optimize a wide range of life history characters including survival, stress resistance, and …

Phenotypic plasticity, the ability for a single genotype to generate different phenotypes in
response to environmental conditions, is biologically ubiquitous, and yet almost nothing is …