Chemical protein modification has emerged as an invaluable tool for the development of
modified proteins. The complementary use of both genetic and chemical methods has …

Engineered liposomal nanoparticles have unique characteristics as cargo carriers in cancer
care and therapeutics. Liposomal theranostics have shown significant progress in preclinical …

Radioimmunotherapy (RIT) aims to selectively deliver radionuclides emitting α-particles, β-
particles or Auger electrons to tumors by conjugation to monoclonal antibodies (mAbs) that …

Adagen, an enzyme replacement treatment for adenosine deaminase deficiency, was the
first protein-polymer conjugate to be approved in early 1990 s. Post this regulatory approval …

Various polymers have been tested for protein conjugation with a goal of bridging the
complementary advantages of both components. However, many of these polymers …

Radiation therapy (RT), including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT), has been an indispensable strategy for cancer therapy in clinical …

Due to their remarkable selectivity and specificity for cancer biomarkers, immunoconjugates
have emerged as extremely promising vectors for the delivery of diagnostic radioisotopes …

Breast cancer is acknowledged as the second most prominent contributor to cancer-related
fatalities among females. The progression of breast cancer involves several sequential …

Inductively coupled plasma mass spectrometry (ICP-MS) with the merits of high sensitivity
and accuracy, strong tolerance to interference and multi-element simultaneous detection …

Polymer conjugation is a clinically proven approach to generate long acting protein drugs
with decreased immune responses. Although poly (ethylene glycol)(PEG) is one of the most …