Gait speed, grip strength, and clinical outcomes in older patients with hematologic malignancies

MA Liu, C DuMontier, A Murillo… - Blood, The Journal …, 2019 - ashpublications.org
This study aimed to evaluate whether gait speed and grip strength predicted clinical
outcomes among older adults with blood cancers. We prospectively recruited 448 patients …

Cell cycle arrest: A breakthrough in the supportive care of older cancer patients

C Falandry, A List, L Balducci - Journal of the American …, 2023 - Wiley Online Library
Background Age is a major risk factor for the acute and chronic complications of cancer
chemotherapy. The current approach to the prevention of these complications is reactive …

Frailty and health-related quality of life in older women with breast cancer

GR Williams, AM Deal, HK Sanoff, KA Nyrop… - Supportive Care in …, 2019 - Springer
Purpose In older women, breast cancer and its treatment can have profound impact on their
physical, mental, and social health, especially in frail patients. This study evaluated the …

The Clinical Frailty Scale can indicate prognosis and care requirements on discharge in oncology and haemato‐oncology inpatients: A cohort study

J Welford, R Rafferty, K Hunt, D Short… - European Journal of …, 2022 - Wiley Online Library
Objectives Routinely used performance status scales, assessing patients' suitability for
cancer treatment, have limited ability to account for multimorbidity, frailty and cognition. The …

[HTML][HTML] Frailty and inflammatory markers in older adults with cancer

TF Nishijima, AM Deal, GR Williams, EJ Guerard… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
We examined the associations between frailty and inflammatory markers, in particular
neutrophil lymphocyte ratio (NLR), in elderly cancer patients. We conducted cross-sectional …

Development of an administrative data-based frailty index for older adults receiving dialysis

RK Hall, S Morton, J Wilson, DH Kim… - Kidney360, 2022 - journals.lww.com
Background Frailty is present in≥ 50% of older adults receiving dialysis. Our objective was
to a develop an administrative data–based frailty index and assess the frailty index's …

Prediction of cognitive decline in older breast cancer survivors: the Thinking and Living with Cancer study

AP McDeed, K Van Dyk, X Zhou, W Zhai… - JNCI Cancer …, 2024 - academic.oup.com
Purpose Cancer survivors commonly report cognitive declines after cancer therapy. Due to
the complex etiology of cancer-related cognitive decline (CRCD), predicting who will be at …

Clinical outcomes associated with anticholinergic burden in older hospitalized patients with advanced cancer: a single-center database study

JH Lee, J Lim, SJ Han, S do Moon, H Moon… - Supportive Care in …, 2021 - Springer
Purpose Although anticholinergic burden has been known to be associated with adverse
outcomes in older adults, its clinical importance has been less studied in patients with …

Optimal frailty dimensions for assessing frailty and predicting chemotherapy adverse events in older Taiwanese cancer patients

YW Ho, SY Chen, YS Hung, SY Lin, WC Chou - Frontiers in Medicine, 2022 - frontiersin.org
Background This study aimed to investigate the effects of different frailty dimensions on
frailty prevalence in older Taiwanese cancer patients receiving chemotherapy, and to …

Research Methods: Translational Research in Geriatric Oncology

GR Williams, HB Muss, SS Shachar - Geriatric Oncology, 2020 - Springer
Cancer is predominantly a disease of aging, and older adults with cancer represent the
majority of cancer diagnoses and deaths in the United States. Despite dramatically …