Transplanting neural progenitor cells to restore connectivity after spinal cord injury
Spinal cord injury remains a scientific and therapeutic challenge with great cost to
individuals and society. The goal of research in this field is to find a means of restoring lost …
individuals and society. The goal of research in this field is to find a means of restoring lost …
Therapeutic potential of neurotrophins for repair after brain injury: a helping hand from biomaterials
J Houlton, N Abumaria, SFR Hinkley… - Frontiers in …, 2019 - frontiersin.org
Stroke remains the leading cause of long-term disability with limited options available to aid
in recovery. Significant effort has been made to try and minimize neuronal damage following …
in recovery. Significant effort has been made to try and minimize neuronal damage following …
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease
M Blurton-Jones, M Kitazawa… - Proceedings of the …, 2009 - National Acad Sciences
Neural stem cell (NSC) transplantation represents an unexplored approach for treating
neurodegenerative disorders associated with cognitive decline such as Alzheimer disease …
neurodegenerative disorders associated with cognitive decline such as Alzheimer disease …
Neuroprotective strategies after neonatal hypoxic ischemic encephalopathy
BJ Dixon, C Reis, WM Ho, J Tang… - International journal of …, 2015 - mdpi.com
Neonatal hypoxic ischemic encephalopathy (HIE) is a devastating disease that primarily
causes neuronal and white matter injury and is among the leading cause of death among …
causes neuronal and white matter injury and is among the leading cause of death among …
Cell-based drug delivery
Drug delivery has been greatly improved over the years by means of chemical and physical
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …
Cell based therapies for ischemic stroke: from basic science to bedside
X Liu, R Ye, T Yan, SP Yu, L Wei, G Xu, X Fan… - Progress in …, 2014 - Elsevier
Cell therapy is emerging as a viable therapy to restore neurological function after stroke.
Many types of stem/progenitor cells from different sources have been explored for their …
Many types of stem/progenitor cells from different sources have been explored for their …
The preventive and therapeutic effects of intravenous human adipose-derived stem cells in Alzheimer's disease mice
S Kim, KA Chang, JA Kim, HG Park, JC Ra, HS Kim… - 2012 - journals.plos.org
Alzheimer's disease (AD) is characterized by the accumulation of amyloid plaques and
neurofibrillary tangles accompanied by cognitive dysfunction. The aim of the present study …
neurofibrillary tangles accompanied by cognitive dysfunction. The aim of the present study …
Cell therapy for neonatal hypoxia–ischemia and cerebral palsy
L Bennet, S Tan, L Van den Heuij, M Derrick… - Annals of …, 2012 - Wiley Online Library
Perinatal hypoxic–ischemic brain injury remains a major cause of cerebral palsy. Although
therapeutic hypothermia is now established to improve recovery from hypoxia–ischemia (HI) …
therapeutic hypothermia is now established to improve recovery from hypoxia–ischemia (HI) …
Drug delivery with living cells
LAL Fliervoet, E Mastrobattista - Advanced drug delivery reviews, 2016 - Elsevier
The field of drug delivery has grown tremendously in the past few decades by developing a
wide range of advanced drug delivery systems. An interesting category is cell-based drug …
wide range of advanced drug delivery systems. An interesting category is cell-based drug …
Functions of neurotrophins and growth factors in neurogenesis and brain repair
The identification and isolation of multipotent neural stem and progenitor cells in the brain,
giving rise to neurons, astrocytes, and oligodendrocytes initiated many studies in order to …
giving rise to neurons, astrocytes, and oligodendrocytes initiated many studies in order to …