[HTML][HTML] Medical image analysis methods in MR/CT-imaged acute-subacute ischemic stroke lesion: Segmentation, prediction and insights into dynamic evolution …

I Rekik, S Allassonnière, TK Carpenter, JM Wardlaw - NeuroImage: Clinical, 2012 - Elsevier
Over the last 15 years, basic thresholding techniques in combination with standard statistical
correlation-based data analysis tools have been widely used to investigate different aspects …

Stroke neuroprotection: targeting mitochondria

L Talley Watts, R Lloyd, R Justin Garling, T Duong - Brain Sciences, 2013 - mdpi.com
Stroke is the fourth leading cause of death and the leading cause of long-term disability in
the United States. Blood flow deficit results in an expanding infarct core with a time-sensitive …

Evolution of the neurochemical profile after transient focal cerebral ischemia in the mouse brain

H Lei, C Berthet, L Hirt… - Journal of Cerebral Blood …, 2009 - journals.sagepub.com
Evolution of the neurochemical profile consisting of 19 metabolites after 30 mins of middle
cerebral artery occlusion was longitudinally assessed at 3, 8 and 24 h in 6 to 8 µL volumes …

Functional, perfusion and diffusion MRI of acute focal ischemic brain injury

Q Shen, H Ren, H Cheng, M Fisher… - Journal of Cerebral …, 2005 - journals.sagepub.com
Combined functional, perfusion and diffusion magnetic resonance imaging (MRI) with a
temporal resolution of 30 mins was performed on permanent and transient focal ischemic …

Neuroprotective efficacy of methylene blue in ischemic stroke: an MRI study

Q Shen, F Du, S Huang, P Rodriguez, LT Watts… - PLoS …, 2013 - journals.plos.org
Methylene blue (MB) has unique energy-enhancing and antioxidant properties and is FDA-
approved drug to treat methemoglobinemia and cyanide poisoning. This study evaluated the …

Spatiotemporal changes in blood-brain barrier permeability, cerebral blood flow, T2 and diffusion following mild traumatic brain injury

W Li, L Watts, J Long, W Zhou, Q Shen, Z Jiang, Y Li… - Brain research, 2016 - Elsevier
The blood-brain barrier (BBB) can be impaired following traumatic brain injury (TBI),
however the spatiotemporal dynamics of BBB leakage remain incompletely understood. In …

The effects of methylene blue on autophagy and apoptosis in MRI-defined normal tissue, ischemic penumbra and ischemic core

Z Jiang, LT Watts, S Huang, Q Shen, P Rodriguez… - PloS one, 2015 - journals.plos.org
Methylene blue (MB) USP, which has energy-enhancing and antioxidant properties, is
currently used to treat methemoglobinemia and cyanide poisoning in humans. We recently …

A review of current imaging methods used in stroke research

HY Wey, VR Desai, TQ Duong - Neurological research, 2013 - Taylor & Francis
Stroke is a serious healthcare problem with high mortality and long-term disability. However,
to date, our ability to prevent and cure stroke remains limited. One important goal in stroke …

Artificial neural network prediction of ischemic tissue fate in acute stroke imaging

S Huang, Q Shen, TQ Duong - Journal of Cerebral Blood …, 2010 - journals.sagepub.com
Multimodal magnetic resonance imaging of acute stroke provides predictive value that can
be used to guide stroke therapy. A flexible artificial neural network (ANN) algorithm was …

Spatiotemporal characteristics of postischemic hyperperfusion with respect to changes in T1, T2, diffusion, angiography, and blood–brain barrier permeability

Q Shen, F Du, S Huang… - Journal of Cerebral Blood …, 2011 - journals.sagepub.com
The spatiotemporal dynamics of postischemic hyperperfusion (HP) remains incompletely
understood. Diffusion, perfusion, T2, T1, angiographic, dynamic susceptibility-contrast …