Ser/Arg-rich (SR) proteins are RNA-binding proteins known as constitutive and alternative
splicing (AS) regulators that regulate multiple aspects of the gene expression program …

Serine/arginine rich splicing factor 3 (SRSF3) is an important multi-functional splicing factor,
and has attracted increasing attentions in the past thirty years. The importance of SRSF3 is …

Alternative RNA splicing is an essential process to yield proteomic diversity in eukaryotic
cells, and aberrant splicing is often associated with numerous human diseases and cancers …

Alternative pre-mRNA splicing expands the coding capacity of eukaryotic genomes,
potentially enabling a limited number of genes to govern the development of complex …

Specific nuclear sub-compartments that are regions of fundamental processes such as gene
expression or DNA repair, contain phosphoinositides (PIPs). PIPs thus potentially represent …

Here, we provide evidence for the presence of Myosin phosphatase rho-interacting protein
(MPRIP), an F-actin-binding protein, in the cell nucleus. The MPRIP protein binds to …

Background Beyond its possible correlation with stemness of tumor cells, CD133/prominin1
is considered an important marker in breast cancer, since it correlates with tumor size …

Inositide‐specific phospholipase Cβ1 (PLCβ1) signaling in cell proliferation has been
investigated thoroughly in the G1 cell cycle phase. However, little is known about its …

The present study describes a complete and detailed neuroanatomical distribution map of
the phospholipase C beta1 (PLCβ1) isoform along the adult rat neuraxis, and defines the …

The AKT/PKB kinase is essential for cell survival, proliferation, and differentiation; however,
aberrant AKT activation leads to the aggressiveness and drug resistance of many human …