Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy
T Pierson, J McArthur… - Annual review of …, 2000 - annualreviews.org
The success of combination antiretroviral therapy for HIV-1 infection has generated interest
in mechanisms by which the virus can persist in the body despite the presence of drugs that …
in mechanisms by which the virus can persist in the body despite the presence of drugs that …
Clinical manifestations and management of antiretroviral nucleoside analog-related mitochondrial toxicity
G Moyle - Clinical therapeutics, 2000 - Elsevier
OBJECTIVES: This article reviews the clinical manifestations of mitochondrial toxicity
associated with the use of nucleoside analog reverse transcriptase inhibitors (NRTIs) and …
associated with the use of nucleoside analog reverse transcriptase inhibitors (NRTIs) and …
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression
RT Davey Jr, N Bhat, C Yoder… - Proceedings of the …, 1999 - National Acad Sciences
Identifying the immunologic and virologic consequences of discontinuing antiretroviral
therapy in HIV-infected patients is of major importance in developing long-term treatment …
therapy in HIV-infected patients is of major importance in developing long-term treatment …
A comparison study of multiple measures of adherence to HIV protease inhibitors
H Liu, CE Golin, LG Miller, RD Hays… - Annals of internal …, 2001 - acpjournals.org
Background: Poor adherence to HIV protease inhibitors may compromise the effectiveness
of treatment. Few studies have compared methods for measuring adherence or have related …
of treatment. Few studies have compared methods for measuring adherence or have related …
Prevalence and predictive value of intermittent viremia with combination HIV therapy
ContextIn HIV-infected patients having virologic suppression (plasma HIV RNA< 50
copies/mL) with antiretroviral therapy, intermittent episodes of low-level viremia have been …
copies/mL) with antiretroviral therapy, intermittent episodes of low-level viremia have been …
Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy
D Descamps, P Flandre, V Calvez, G Peytavin… - Jama, 2000 - jamanetwork.com
ContextIn the Trilège trial, following induction with a zidovudine, lamivudine, and indinavir
regimen, human immunodeficiency virus (HIV) replication was less suppressed by 2-drug …
regimen, human immunodeficiency virus (HIV) replication was less suppressed by 2-drug …
Maintenance antiretroviral therapies in HIV-infected subjects with undetectable plasma HIV RNA after triple-drug therapy
DV Havlir, IC Marschner, MS Hirsch… - … England Journal of …, 1998 - Mass Medical Soc
Background Combination antiretroviral therapy with indinavir, zidovudine, and lamivudine
can suppress the level of human immunodeficiency virus (HIV) RNA in plasma below the …
can suppress the level of human immunodeficiency virus (HIV) RNA in plasma below the …
Reversion of metabolic abnormalities after switching from HIV-1 protease inhibitors to nevirapine
E Martínez, I Conget, L Lozano, R Casamitjana… - Aids, 1999 - journals.lww.com
Objectives: To assess the effects of switching from HIV-1 protease inhibitors (PI) to
nevirapine on metabolic abnormalities in patients with fat redistribution and on CD4 T …
nevirapine on metabolic abnormalities in patients with fat redistribution and on CD4 T …
Highly active antiretroviral therapy (HAART) for the treatment of infection with human immunodeficiency virus type 1
RW Shafer, DA Vuitton - Biomedicine & pharmacotherapy, 1999 - Elsevier
Highly active antiretroviral therapy (HAART) refers to a broad category of treatment regimens
usually comprised of three or more antiretroviral drugs that, in previously untreated HIV-1 …
usually comprised of three or more antiretroviral drugs that, in previously untreated HIV-1 …
Dual therapy treatment strategies for the management of patients infected with HIV: a systematic review of current evidence in ARV-naive or ARV-experienced …
JG Baril, JB Angel, MJ Gill, J Gathe, P Cahn… - PLoS …, 2016 - journals.plos.org
Objective We reviewed the current literature regarding antiretroviral (ARV)-sparing therapy
strategies to determine whether these novel regimens can be considered appropriate …
strategies to determine whether these novel regimens can be considered appropriate …